Results 121 to 130 of about 3,095,027 (298)

ENGINEERING AND TECHNOLOGY IN INDUSTRIAL CIVILIZATION CULTURE

open access: yesAdvanced Engineering Research, 2012
Both internal logic of the engineering and technolo gy development, and their sociocultural aspect is analyzed. The concepts under study are considered in connection with the existence, activity, values of the society.
Evgeny I. Sedov, Artur E. Sedov
doaj  

Experimental determination of the structure of shock waves in fluid flow through collapsible tubes with application to the design of a flow regulator

open access: yes, 1979
Thesis: Mech. E., Massachusetts Institute of Technology, Department of Mechanical Engineering, 1979Includes bibliographical references.by Ifiyenia Kececioglu.Mech. E.Mech. E.
Kececioglu, Ifiyenia.
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

World Journal of Engineering and Technology

open access: yes, 2013
World Journal of Engineering and Technology (WJET) is an open access journal published quarterly. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various issues and ...
DE MIRANDA, STEFANO
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

ENGINEERING AND TECHNOLOGY IN INDUSTRIAL CIVILIZATION CULTURE

open access: yesВестник Донского государственного технического университета, 2018
Both internal logic of the engineering and technolo gy development, and their sociocultural aspect is analyzed. The concepts under study are considered in connection with the existence, activity, values of the society.
Evgeny I. Sedov, Artur E. Sedov
doaj  

Technology adoption in automotive product development

open access: yes, 2014
Thesis: S.M. in Engineering and Management, Massachusetts Institute of Technology, Engineering Systems Division, 2014.Cataloged from PDF version of thesis.Includes bibliographical references (pages 46-50).The automotive industry is characterized by the ...
Pinto, Alejandro, S.M. Massachusetts Institute of Technology
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Modern Education Technology with Creativity of Continuing Education

open access: yes, 2008
This presentation was part of the session : Technology to Support Instructors, Part 1IACEE 11th World Conference on Continuing Engineering EducationLuo Long is the research assistant of Continuing Education School of Tsinghua University.
Gengsheng, Wu   +3 more
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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