Results 61 to 70 of about 573,134 (292)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
The potential of additive manufacturing in the smart factory industrial 4.0: A review [PDF]
, 2019 Additive manufacturing (AM) or three-dimensional (3D) printing has introduced a novel production method in design, manufacturing, and distribution to end-users.
Dehghanghadikolaei, Amir +5 more
core +1 more source
Enhancing Scientific Communication Skills: a Real-World Simulation in a Tertiary-Level Life Science Class Using E-Learning Technology in Biomedical Literature Perception, Reflective Review Writing on a Clinical Issue, and Self and Peer Assessments [PDF]
Research in Science Education, 2018 This educational study aimed to explore the feasibility and acceptance of a literacy exercise adopted from the realworld of scientific publishing in a cell and tissue biology course. For that purpose, a tertiary-level multimodality science course, which integrated a blended learning faculty and student lectures, journal club, and wet laboratory ...
Elisabeth Eppler +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Revista Peruana de Medicina Experimental y Salud PúblicaObjetivos. Evaluar la aceptabilidad y factibilidad de una intervención basada en salud móvil, para la adopción de estilos de vida saludables en personas prehipertensas que viven en zonas urbanas de bajos recursos en Argentina, Guatemala y Perú ...
Andrea Beratarrechea +8 more
doaj +2 more sources
Guest Editorial: The 2014 Capstone Design Conference [PDF]
, 2015 The goal of the 2014 Capstone Design Conference held in Columbus, OH was to build upon the success of three previous conferences (2007 and 2010 in Boulder, CO, and 2012 in Champaign, IL) and expand the community of educators, students, and industry ...
Beyerlein, Steven +5 more
core +1 more source
Universal in vivo Textural Model for Human Skin based on Optical Coherence Tomograms
, 2017 Currently, diagnosis of skin diseases is based primarily on visual pattern recognition skills and expertise of the physician observing the lesion. Even though dermatologists are trained to recognize patterns of morphology, it is still a subjective visual
Adabi, Saba +7 more
core +2 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Environment International, 2020 Inhalation from ambient air and cigarette smoke is a common route of human exposure to polycyclic aromatic hydrocarbons (PAHs). Little information is available regarding hepatotoxicities of inhaled PAHs so for.
Fang Li +7 more
doaj +1 more source
Actual metrological conditions for ionizing chamber calibration in radiotherapy [PDF]
Archive of Oncology, 2004 BACKGROUND: Since 1976 it has been recognized that an accuracy of ±5% in the delivery of an absorbed dose to a target volume is necessary for successful therapy treatment.
Spasić-Jokić Vesna M.
doaj +1 more source