Results 71 to 80 of about 876,316 (262)

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

FEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui, Ariel Kushmaro, Hana Barak, Anja Poehlein, Rolf Daniel, Hans‐Jürgen Mägert   +5 more
wiley   +1 more source

Advanced Refrigerator/Freezer Technology Development Project [PDF]

The Advanced Refrigerator/Freezer (R/F) Technology Development Project was initiated in 1994, on the basis of recommendations of a team of NASA Scientists and engineers, who assessed the need for advanced technology to support future life and biomedical ...
Cairelli, James E., Geng, Steven M.
core   +1 more source

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source

Improvement of medical content in the curriculum of biomedical engineering based on assessment of students outcomes

BMC Medical Education, 2017
Improvement of medical content in Biomedical Engineering curricula based on a qualitative assessment process or on a comparison with another high-standard program has been approached by a number of studies. However, the quantitative assessment tools have
E. Abdulhay, R. Khnouf, Shireen Haddad, Areen K. Al-Bashir   +3 more
semanticscholar   +1 more source

Guest Editorial: The 2014 Capstone Design Conference [PDF]

, 2015
The goal of the 2014 Capstone Design Conference held in Columbus, OH was to build upon the success of three previous conferences (2007 and 2010 in Boulder, CO, and 2012 in Champaign, IL) and expand the community of educators, students, and industry ...
Beyerlein, Steven, Goldberg, Jay R., Howe, Susannah, Palo, Scott, Rogge, Renee, Stanfill, R. Keith   +5 more
core   +1 more source

A comparative analysis of deep learning architectures with data augmentation and multichannel input for locoregional breast cancer radiotherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Studies on deep learning dose prediction increasingly focus on 3D models with multiple input channels and data augmentation, which increases the training time and thus also the environmental burden and hampers the ease of re‐training. Here we compare 2D and 3D U‐Net models with clinical accepted plans to evaluate the appropriateness of
Rosalie Klarenberg, Nienke L. M. Bakx, Coen W. Hurkmans   +2 more
wiley   +1 more source

Immersive virtual reality-based learning as a supplement for biomedical engineering labs: challenges faced and lessons learned

Frontiers in Medical Technology
Introduction Immersive virtual reality (VR) based laboratory demonstrations have been gaining traction in STEM education as they can provide virtual hands-on experience.
Ishita Tandon, Vitali V. Maldonado, Megan Wilkerson, Amanda Walls, Rajee Rao, Mostafa Elsaadany   +5 more
semanticscholar   +1 more source

Comprehensive Health Care Reform and Biomedical Innovation [PDF]

, 2008
Considers ways to control the costs of development, adoption, and diffusion of new technologies as part of comprehensive healthcare reform.
Ezekiel J. Emanuel
core  

Comprehensive clinical evaluation of novel 4DCT‐based lung function imaging methods

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Methods have been developed that apply image processing to 4DCTs to generate 4DCT‐ventilation/perfusion lung imaging. Traditional methods for 4DCT‐ventilation rely on Hounsfield‐Unit (HU) density‐change methods and suffer from poor numerical robustness while not providing 4DCT‐perfusion data.
Ehsan Golkar, Taindra Neupane, Lydia Wilson, Jennifer Kwak, Richard Castillo, Edward Castillo, Yevgeniy Vinogradskiy   +6 more
wiley   +1 more source