Results 81 to 90 of about 573,134 (292)

Wearable Biomedical Measurement Systems for Assessment of Mental Stress of Combatants in Real Time

Sensors, 2014
The Spanish Ministry of Defense, through its Future Combatant program, has sought to develop technology aids with the aim of extending combatants’ operational capabilities.
Fernando Seoane, Inmaculada Mohino-Herranz, Javier Ferreira, Lorena Alvarez, Ruben Buendia, David Ayllón, Cosme Llerena, Roberto Gil-Pita   +7 more
doaj   +1 more source

Developing the Quantitative Histopathology Image Ontology : A case study using the hot spot detection problem [PDF]

, 2017
Interoperability across data sets is a key challenge for quantitative histopathological imaging. There is a need for an ontology that can support effective merging of pathological image data with associated clinical and demographic data.
Doyle, Scott, Gurcan, Metin, James, A., John, Overton, N., Tomaszewski, Ruttenberg, Alan, Smith, Barry   +6 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Does the broad dissemination of end-of-life letters for medical devices, including in a national repository, contribute to the implementation of the National Policy on Health Technology Management?

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia
Introduction: Medical device End-of-Life (EOL) and End-of-Service (EOS) letters, or discontinuation notices, informing the cessation of production and the timeline for technical support, are essential for planning replacement, as well as preventive and ...
Fotini Santos Toscas, Bruno Andreas Sousa de Camargo da Veiga Roma, Roberto Souza, Fernanda Carvalho Vieira, Evelinda Marrom Trindade   +4 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Growth Characteristic of Fungus strain MGS-2 in a Defined Medium Containing Organic Acids Derived from Peat Soil

Microbiology Indonesia, 2014
Some organic acids derived from lignin degradation in peat soil have significant role in lowering pH of peat soil and have phytotoxic effect for plant.
DIANA NURANI, KOESNANDAR KOESNANDAR
doaj   +1 more source

Somatosensory and nociceptive changes in chronic post-stroke shoulder pain [PDF]

, 2008
Preliminary results from a cross-sectional study that investigated the relation between the presence of post-stroke shoulder pain and somatosensory and nociceptive changes are presented.
Buitenweg, J.R., Dongen, R.T.M. van, Geurts, A.C.H., IJzerman, M.J., Renzenbrink, G.J., Roosink, M.   +5 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Avanços e desafios da política nacional de gestão de tecnologias em saúde

Revista de Saúde Pública
O Ministério da Saúde instituiu dois processos articulados no campo da gestão de tecnologias em saúde: (i) produção, sistematização e difusão de estudos de avaliação de tecnologias em saúde e (ii) adoção de um fluxo para incorporação, exclusão ou ...
Hudson P Silva, Clarice A Petramale, Flavia T S Elias   +2 more
doaj  

Horizon scanning in Brazil: outputs and repercussions

Revista de Saúde Pública, 2019
OBJECTIVE: To describe the four types of horizon scanning (HS) outputs developed by the National Committee for Health Technology Incorporation (CONITEC) and show their main repercussions on the decision-making processes of the Brazilian Ministry of ...
Pollyanna Teresa Cirilo Gomes, Verónica Elizabeth Mata, Thais Conceição Borges, Dayani Galato   +3 more
doaj   +2 more sources