Thalamocortical regulation of prefrontal stability enables abstract rule generalization. [PDF]
Wang Z +9 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Dish-Choice, a Three-Color Food Label, Improves Subjective Perceptions of Nutrition Information Among Chinese Diners Compared with a Standard Nutrition Facts Label: A Self-Controlled Survey. [PDF]
Yu J +13 more
europepmc +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Exploring the relationship between delay discounting and physical activity: a meta-analysis of continuous associations. [PDF]
Tan F, Jiao Z, Guo K, Fu H.
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Event Source Modulates the Valence Focus of Optimism Bias: Evidence from Behavior and ERPs. [PDF]
Wang C, Zhang B, Ren J.
europepmc +1 more source
Performance of Large Language Models in the Japanese Public Health Nurse National Examination: Comparative Cross-Sectional Study. [PDF]
Takahashi Y +3 more
europepmc +1 more source
Comparing Stakeholders' Perspectives on Parkinson Disease Management and Digital Technologies: Exploratory International Survey. [PDF]
Luckhaus JL +11 more
europepmc +1 more source

