Results 51 to 60 of about 603,404 (263)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Factors Affecting Discipline Choice in Students of Medical Records and Health Information Technology in Mazandaran University of Medical Sciences in Year 2010 [PDF]
مجله ایرانی آموزش در علوم پزشکی, 2012 Introduction: Higher education administrators believe that discipline choice method could be an important motivator to continue study. The field of health information technology in BS level which is a specialized field in health area was introduced by ...
Azar kabirzadeh +3 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Radio-frequency electrosurgery as the ultimate choice technology of cervical cancer prevention
Медицинский совет, 2013 Cervical cancer (CC) is the second most common type of cancer among females. In 2008, the diagnosis was a death sentence to 247,883 women. In total, 529,409 new cases were registered, accounting for 13% of the total number of malignant diseases of women ...
V. E. Radzinskiy, R. Yu. Yeremichev
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
A study of medical professionals’ perspectives on medicines containing codeine in South Africa
South African Journal of Psychiatry, 2018 Background: Misuse of codeine available on prescription and over-the-counter (OTC) has been highlighted as a potential problem in South Africa. Objective: To examine the perceptions of medical professionals regarding codeine use (prescribed and OTC ...
Michelle Foley +5 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
CHOICE OF MATERIAL AND MANUFACTURING TECHNOLOGY OF CASTING
Литьë и металлургия, 2016 As a result of the carried out work abundant type of steel was chosen for casting production of asterisk of the excavator «Kamatsu». This type of steel is widely used as the wearproof steel working in the conditions of abrasive and shock – abrasive wear.
L. I. Kupriyanova, O. M. Shikurov
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