Results 141 to 150 of about 899,857 (269)

Performance Measurement of the PeopleSoft Multi-Tier Remote Computing Application [PDF]

open access: yes, 1998
The Center for Information Technology Integration has undertaken a study of the potential impact of PeopleSoft software on U-M production computing environments, focusing on the measurement and modeling of the Peoplesoft 6 architecture in order to ...
Teorey, Toby J.   +5 more
core  

Systemic model for technology integration in teaching. [PDF]

open access: yesEduc Inf Technol (Dordr), 2022
Peled Y, Perzon S.
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

A 3.584 Tbps coherent receiver chip on InP-LiNbO3 wafer-level integration platform

open access: yesLight: Science & Applications
The rapid advancement of the thin-film lithium niobate (LiNbO3) platform has established it as a premier choice for high-performance photonics integrated circuits. However, the scalability and cost-efficiency of this platform are hindered by the reliance
Xiaojun Xie   +10 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Effective and Engaging OR Pointless and Problematic? Integrating Technology into the High School History Classroom

open access: yes, 2017
This research study explored how a sample of high school History teachers in Ontario are integrating technology into their classrooms. The study was conducted using a qualitative research approach that involved reviewing the relevant literature and ...
Reda, Francesca Danielle
core  

Pluggable Authentication Module for Windows NT [PDF]

open access: yes, 1998
To meet the challenge of integrating new methods and technologies into the Internet security framework, it is useful to hide low-level authentication mechanisms from application programmers, system administrators, and users, replacing them with ...
Peter Honeyman   +3 more
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

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