Results 61 to 70 of about 1,281,035 (364)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Assessing the impact of an innovative community of practice on teacher efficacy, leadership and practice [PDF]
, 2017 Dissertation supervisor: Dr. James Laffey.Includes vita.The purpose of this study was to determine how participation in a Community of Practice impacted technology teacher leadership and technology integration practice. Participants in the study included
Williams, MaryShannon
core +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Digital learning objects: A need for educational leadership [PDF]
, 2009 Despite increasing interest in technology-assisted education, technology-based instructional design still lacks support from a reliable body of empirical research. This dearth of reliable information hampers its integration into mainstream school systems.
Annick, Janson +2 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Social Sciences and Humanities OpenThis study explores the complex relationship between technology and leadership in education. Four major themes emerged from the qualitative methodology used to interview 161 people holding leadership positions in education: communication and ...
Afam Uzorka, Kagezi Kalabuki
doaj +1 more source
ASCILITE Publications, 2010 While research has found that technology leadership is an important factor for effective integration of technology in schools, there is a paucity of research on technology leadership in schools. This paper reviewed 12 empirical reports on technology leadership and a grounded theory approach was used to derive the key findings.
openaire +1 more source
Determining how information technology is changing the role of leadership in virtual organization [PDF]
, 2001 Includes bibliographical ...
Al-jedaibi, Hani K.
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source