Results 251 to 260 of about 671,207 (363)

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

Correcting Apparent Priming Bias Unveils Fertilizer Nitrogen‐Risk Archetypes of Surplus and Depletion Across Asian Rice Systems

Advanced Science, EarlyView.
Correcting the apparent priming effect resolves systematic biases in Asian rice fertilizer nitrogen accounting. Net soil retention drops below 7%, while 48% of fertilizer escapes, inflicting US$98.53 billion in annual reactive‐nitrogen damages. High‐resolution mapping uncovers N‐risk archetypes across 42% of the rice area, delivering a spatially ...
Xiuyun Liu, Siyuan Cai, Longlong Xia, Jagdish K. Ladha, Xiaoyuan Yan, Xu Zhao   +5 more
wiley   +1 more source

China's regulatory regime for medical biotechnology: evolution, challenges, and future perspectives. [PDF]

Front Med Technol
Zhang E.
europepmc   +1 more source

Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276

Advanced Science, EarlyView.
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan, Ruimin Chang, Meng Zhang, Qian Dong, Guanxiong Zhang, Xiang Chen, Mingliang Chen, Lixia Lu, Xiaowei Liang, Yeye Guo, Juan Su   +10 more
wiley   +1 more source

Assessing National Health Research System in a resource-limited setting: Insights from Indonesia. [PDF]

PLoS One
Dharmawan T, Sutoyo DA, Qorina F, Gamalliel N, Kurniawan M, Kusuma D, Fuady A.   +6 more
europepmc   +1 more source

Interfacial Control in Cu–MXene Hybrids Enables Selective NOx‐to‐NH3 Electroconversion: A Critical Review

Advanced Science, EarlyView.
Cu‐MXene interfacial catalysts provide a promising platform for electrochemical NOx upcycling to ammonia. The synergy between Cu active sites and conductive, surface‐tunable MXene supports promotes NOx adsorption, intermediate stabilization, and selective NH3 formation while suppressing competing hydrogen evolution, offering a route toward sustainable ...
Hafiz Muhammad Adeel Sharif, Gechuanqi Pan, Yuwei Wang, Yasir Abbas, Asif Mahmood, Changping Li   +5 more
wiley   +1 more source

The Italian Stance on Robotic Surgery: A Paradigm Shift in Health Technology Assessment Governance. [PDF]

Lancet Reg Health Eur
Levi Sandri GB.
europepmc   +1 more source

Terahertz Channel Modeling, Estimation and Localization in RIS‐Assisted Systems

Advanced Electronic Materials, EarlyView.
Reconfigurable intelligent surfaces have become a recent intensive research focus. Based on practical applications, channel strategies for RIS‐assisted terahertz wireless communication systems are categorized into three different types: channel modeling, channel estimation, and channel localization.
Hongjing Wang, Weipeng Wang, Xuan Cong, Shiyu Wang, Gao Li, Sen Gong, Lin Huang, Hongxin Zeng, Yaxin Zhang, Ziqiang Yang   +9 more
wiley   +1 more source

Spatial spillovers, mediating mechanisms and moderating effects of industrial agglomeration in promoting green total factor productivity. [PDF]

Sci Rep
Zhong C, Yin J, Ibrahim S, Zhang X, Mao X.   +4 more
europepmc   +1 more source

Technological innovations used to overcome the problem of resource scarcity in small - scale enterprises : implications for policy

, 1999
Ngahu, C.W., African Technology Policy Studies Network   +1 more
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