Results 21 to 30 of about 3,253,965 (265)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

TEKNOLOJİ POLİTİKALARI VE TÜRKİYE: BİR İNCELEME

Sosyal Ekonomik Araştırmalar Dergisi, 2008
Bu çalışma Avrupa Topluluğuna girmeyi amaçlayan Türkiye için optimal bir teknoloji politika çerçevesi oluşturmak için dünyadaki teknoloji politikaları arasında bir karşılaştırma yapmak amacındadır.
İsmail Seyrek, Murat Sarıkaya
doaj   +2 more sources

Low-carbon technology for the rising middle class [PDF]

, 2013
This policy brief will discuss the role of local and international technology and innovation policies for low-carbon development of the rising middle class in developing countries.
Byrne, Robert, de Coninck, Heleen
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Science, Technology and U.S. Economic Policy [PDF]

, 1986
Volume 3 - Paper #44_44ScienceTechnologyandUSeconomical.pdf: 194 downloads, before Oct.
Briggs, Vernon M., Jr.
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Universal Basic AI Access: Countering the Digital Divide

Acta Informatica Pragensia
Generative artificial intelligence (GAI) presents an opportunity to democratize access to high-performance, easy-to-use tools of productivity enhancement.
Petr Špecián, Jitka Špeciánová
doaj   +1 more source

Cybersecurity Implications of Quantum Computing and Its Combined Use with Artificial Intelligence [PDF]

Revista UNISCI
Quantum computing presents new market opportunities, but also significant challenges, particularly in areas such as cybersecurity. Although still in its infancy, quantum computing is maturing rapidly.
Andrea G. Rodriguez
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

How Does Government Policy Improve Green Technology Innovation: An Empirical Study in China

Frontiers in Environmental Science, 2022
This paper divides government policy according to policy quantity, policy effectiveness and policy executive force so that the government policy can be quantified in more detail.
Guancen Wu, Qian Xu, Xing Niu, Li Tao
doaj   +1 more source