Results 221 to 230 of about 298,273 (258)

A Strategic Roadmap to Support Communication on and Acceptance of Surrogate Endpoints: The REnal Surrogacy accEpTance in Chronic Kidney Disease (RESET CKD) Collaboration. [PDF]

Adv Ther
Garcia Sanchez JJ, Trapero-Bertran M, Ciani O, Detournay B, Gesualdo L, Heerspink HJL, Inker LA, Sinha S, Wanner C, Little DJ, Sinsakul M, Nam YS, Taylor RS.   +12 more
europepmc   +1 more source

Integrative Single‐Cell RNA Sequencing and Spatial Transcriptomics Uncover Distinct Fibroblast–Macrophage Crosstalk in Human Hip Synovium Between Patients With Femoroacetabular Impingement and Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell–cell interactions in FAI and hip OA.
Gulzada Kulzhanova, Alexis Klee, Mina Botros, Victoria L. Hansen, John Reuter, Eliya Tazreena Tashbib, Eloise Fadial, Benjamin F. Ricciardi, Brian Giordano, Chia‐Lung Wu   +9 more
wiley   +1 more source

AI-Driven Career Guidance to Reduce Vocational Students' Career Path Anxiety through Skills Mapping, Adaptive Mentoring, and Labor Market Intelligence. [PDF]

F1000Res
Wahrini R, Hasbi H, Nuruzzaman M, Nur NA, Budiastuti P, Gaspersz M, Tanggu Mara A.   +6 more
europepmc   +1 more source

Integrating generative AI and physical tests to strengthen claims about emergent phenomena. [PDF]

Proc Natl Acad Sci U S A
Cheng W, Yu Z.
europepmc   +1 more source

Designing the MyoFusion Media: A Serum‐Free Medium Optimized for Bovine Satellite Cell Differentiation

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Cultivated meat production requires efficient differentiation of muscle progenitor cells into myotubes without relying on animal‐derived serum, which poses ethical and scalability challenges. This study aimed to develop a chemically defined, serum‐free medium optimized for bovine satellite cell differentiation.
Aysenaz Tavsanli, Viktor Milkevych, Jette Feveile Young, Martin Krøyer Rasmussen   +3 more
wiley   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

BMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam, Xiaojun Cai, Malik Ihsan Ullah Khan, Robert Musiol, Quazi T. H. Shubhra   +4 more
wiley   +1 more source

Bio-inspired cognitive robotics vs. embodied AI for socially acceptable, civilized robots. [PDF]

Front Robot AI
Morasso P.
europepmc   +1 more source

A new era for ICU-acquired weakness research-from mechanisms to meaningful recovery. [PDF]

Intensive Care Med
Piva S, Langouche L, Mohammed A.
europepmc   +1 more source

From pilot to policy: why AI health interventions fail to scale in developing countries. [PDF]

Front Digit Health
Joseph J.
europepmc   +1 more source