Results 121 to 130 of about 830,933 (313)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Evaluating the effect of phosphogypsum source and rate on barley yield components, nutrients uptake, and heavy metals content under saline conditions

Discover Agriculture
Background Soil salinity is a major factor in land degradation, affecting one billion hectares worldwide. Several strategies for overcoming salinity stress have been tested.
M Barka Outbakat, Moussa Bouray, Mohamed El Gharous, Kamal El Omari, Khalil El Mejahed   +4 more
doaj   +1 more source

Medical Device Development from Ideation to Regulation and Technology Transfer in Low- and Middle-income Countries. [PDF]

Acta Med Philipp, 2023
De Leon RP, Tejero LMS.
europepmc   +1 more source

The Role of Technology Maturity Level in the Occurrence of University Technology Transfer

, 2023
Malcolm Townes
openalex   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

A technology transfer journey to a model-driven access control system. [PDF]

Int J Softw Tools Technol Transf, 2023
De Sanctis M, Di Salle A, Iovino L, Rossi MT.   +3 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Multivariate Pharma Technology Transfer Analysis: Civilization Diseases and COVID-19 Perspective. [PDF]

Int J Environ Res Public Health, 2023
Śledzik K, Płoska R, Chmielewski M, Barembruch A, Szmelter-Jarosz A, Kędzierska-Szczepaniak A, Antonowicz P.   +6 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

P13-A113 The EVEIT bioreactor system as platform for artificial cornea prototypes

BMJ Open Ophthalmology, 2023
Norbert Schrage, Markus Glaudo, Claudia Panfil   +2 more
doaj   +1 more source