Results 121 to 130 of about 833,836 (267)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

P13-A113 The EVEIT bioreactor system as platform for artificial cornea prototypes

BMJ Open Ophthalmology, 2023
Norbert Schrage, Markus Glaudo, Claudia Panfil   +2 more
doaj   +1 more source

Vaccine technology transfer in a global health crisis: Actors, capabilities, and institutions. [PDF]

Res Policy, 2023
Fonseca EMD, Shadlen KC, Achcar HM.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Does high-speed rail stimulate university technology transfer? evidence from China. [PDF]

PLoS One, 2023
Wu X, Luo H, Wu Y.
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

A technology transfer journey to a model-driven access control system. [PDF]

Int J Softw Tools Technol Transf, 2023
De Sanctis M, Di Salle A, Iovino L, Rossi MT.   +3 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Correction: A decade of Cybathlon: impact on public visibility, scientific dissemination and technology transfer. [PDF]

J Neuroeng Rehabil
Riener R, Vassella L, Wolf P.
europepmc   +1 more source

Medical Device Development from Ideation to Regulation and Technology Transfer in Low- and Middle-income Countries. [PDF]

Acta Med Philipp, 2023
De Leon RP, Tejero LMS.
europepmc   +1 more source