Results 151 to 160 of about 3,418,997 (346)

Multivariate Pharma Technology Transfer Analysis: Civilization Diseases and COVID-19 Perspective. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Śledzik K   +6 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

The space exploration initiative. Operational efficiency panel space-basing technology requirements [PDF]

open access: yes
The topics covered include the following: (1) space basing technology requirements sources; (2) orbit transfer vehicle (OTV) processing heritage; (3) ground processing progression to space processing; (4) technology requirements for space based OTV ...
Pena, Luis R.
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

P13-A113 The EVEIT bioreactor system as platform for artificial cornea prototypes

open access: yesBMJ Open Ophthalmology, 2023
Norbert Schrage   +2 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Vaccine innovation model: A technology transfer perspective in pandemic contexts. [PDF]

open access: yesVaccine, 2022
Medeiros MZ   +5 more
europepmc   +1 more source

Training need of agricultural input dealers for transfer of technology

open access: bronze, 2015
Pratik Shelake   +3 more
openalex   +1 more source

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