Results 41 to 50 of about 362,572 (195)
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
El Grupo De Iguales En La Formación De Habilidade Sociales
Xihmai, 2012 Nadie se hace humano solo. Sólo el contacto, el contagio de otros seres humanos, nos hace humanos...Y por eso la buena educación es fabricación de humanidad (Fernando Savater) Resumen El propósito de esta reflexión es señalar la ...
María Juana Berra Bortolotti +1 more
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Tecnología para la enseñanza y el aprendizaje de lenguas extranjeras: revisión de la literatura
, 2019 En plena era de revolucion tecnologica, las tecnologias y su buen uso y consumo asi como la capacidad de comunicarse en una o varias segundas lenguas contribuyen a la conexion de los habitantes de este mundo globalizado; nuestros espacios comunicativos ...
F. Sáez +2 more
semanticscholar +1 more source
Ciência & Educação, 2019 Resumo: A problematização da suposta neutralidade da Ciência-Tecnologia para a constituição de uma cultura de participação em processos decisórios é fundamental.
R. Santos, Décio Auler
semanticscholar +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Revista Electrónica de AnestesiaR, 1970 Este estudio compara las características de intubación de 2 laringoscopios distintos: el clásico de Macintosh (MAC) y el vídeolaringoscopio Glidescope (GLD), en la colocación de tubos de doble luz (TDL) izquierdos en cirugías que precisaban aislamiento ...
Enrique Juez Núñez +2 more
doaj +1 more source
APRENDIZAGEM MEDIADA PELA TECNOLOGIA
, 2017 O texto analisa a relacao entre tecnologia e aprendizagem. Inicia pela compreensao de que o uso das tecnologias disponiveis, em cada epoca da historia da humanidade, transforma radicalmente a forma de organizacao social, comunicacao, cultura e a ...
V. M. Kenski
semanticscholar +1 more source
Debates sobre Tecnología y Educación: Caminos contemporáneos y conversaciones pendientes
RIED: Revista Iberoamericana de Educación a Distancia, 2019 El objetivo de este número especial de RIED es contribuir a promover procesos críticos de transformación en el ámbito de la Tecnología Educativa, a través de una colección de nueve artículos que consiguen hacer, a la vez, un estado de la cuestión y un ...
L. Castañeda
semanticscholar +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source