Proapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cells [PDF]
Malignant gliomas are characterized by an intrinsic ability to invade diffusely throughout the normal brain tissue. This feature contributes mainly to the failure of existing therapies. Deregulation of small GTPases signaling, in particular Rac1 activity,
Alonso, Daniel Fernando+7 more
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Ornithodoros quilinensis sp. nov. (Acari, Argasidae), a new tick species from the Chacoan region in Argentina [PDF]
Ornithodoros quilinensis sp. nov. (Acari: Argasidae) is described from larvae collected on the small rodents Graomys centralis (Cricetidae: Sigmodontinae) in Argentina.
Casás, Gustavo+5 more
core +1 more source
Clutch size of Caiman latirostris (Crocodylia: Alligatoridae) varies on a latitudinal gradient [PDF]
The distribution of the Broad-Snouted Caiman (Caiman latirostris) ranges from 5°S to 32°S. Thus, caiman populations are exposed to different climatic conditions, and this latitudinal gradient could affect aspects of their reproduction.
Piña, Carlos Ignacio+2 more
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This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
Field-Assisted and Thermionic Contributions to Conductance in SnO2 Thick-Films [PDF]
A deep analysis of conductance in nanostructured SnO2 thick films has been performed. A model for field-assisted thermionic barrier crossing is being proposed to explain the film conductivity.
Aldao, Celso Manuel+5 more
core +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
Layered double hydroxides-indomethacin nanohybrids: intercalation, pH influence, stability and release properties [PDF]
In this work, three pH values (8, 9 and 10) were studied for the insertion of Indomethacin (Indo) molecules into Layered Double Hydroxides (LDHs). The obtained results showed that the LDH materials have been a good storage for the drug.
Crivello, Mónica Elsie+6 more
core +1 more source
Morphology of copper deposits obtained by metallic electrodeposition [PDF]
Electrochemical deposition of copper from copper nitrate aqueous electrolyte on graphite substrate was investigated at current densities between 0.03 mA/cm2 - 1.36 mA/cm2 and in the voltage range of 3 V to 15 V.
Brunetti, Veronica+4 more
core +1 more source
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez+8 more
wiley +1 more source
Notas sobre la nidificación del Chopí (Gnorimopsar chopi) en Argentina y Paraguay, con datos de cría cooperativa y de parasitismo de cría por el Tordo Pico Corto (Molothrus rufoaxillaris) [PDF]
Fil: Fraga, Rosendo Manuel. Provincia de Entre Ríos. Centro de Investigaciones Científicas y Transferencia de Tecnología a la Producción. Universidad Autónoma de Entre Ríos.
Fraga, Rosendo Manuel
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