Results 21 to 30 of about 1,423,105 (342)

Proapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cells [PDF]

open access: yes, 2014
Malignant gliomas are characterized by an intrinsic ability to invade diffusely throughout the normal brain tissue. This feature contributes mainly to the failure of existing therapies. Deregulation of small GTPases signaling, in particular Rac1 activity,
Alonso, Daniel Fernando   +7 more
core   +2 more sources

Ornithodoros quilinensis sp. nov. (Acari, Argasidae), a new tick species from the Chacoan region in Argentina [PDF]

open access: yes, 2012
Ornithodoros quilinensis sp. nov. (Acari: Argasidae) is described from larvae collected on the small rodents Graomys centralis (Cricetidae: Sigmodontinae) in Argentina.
Casás, Gustavo   +5 more
core   +1 more source

Clutch size of Caiman latirostris (Crocodylia: Alligatoridae) varies on a latitudinal gradient [PDF]

open access: yes, 2009
The distribution of the Broad-Snouted Caiman (Caiman latirostris) ranges from 5°S to 32°S. Thus, caiman populations are exposed to different climatic conditions, and this latitudinal gradient could affect aspects of their reproduction.
Piña, Carlos Ignacio   +2 more
core  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Field-Assisted and Thermionic Contributions to Conductance in SnO2 Thick-Films [PDF]

open access: yes, 2009
A deep analysis of conductance in nanostructured SnO2 thick films has been performed. A model for field-assisted thermionic barrier crossing is being proposed to explain the film conductivity.
Aldao, Celso Manuel   +5 more
core   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Layered double hydroxides-indomethacin nanohybrids: intercalation, pH influence, stability and release properties [PDF]

open access: yes, 2016
In this work, three pH values (8, 9 and 10) were studied for the insertion of Indomethacin (Indo) molecules into Layered Double Hydroxides (LDHs). The obtained results showed that the LDH materials have been a good storage for the drug.
Crivello, Mónica Elsie   +6 more
core   +1 more source

Morphology of copper deposits obtained by metallic electrodeposition [PDF]

open access: yes, 2015
Electrochemical deposition of copper from copper nitrate aqueous electrolyte on graphite substrate was investigated at current densities between 0.03 mA/cm2 - 1.36 mA/cm2 and in the voltage range of 3 V to 15 V.
Brunetti, Veronica   +4 more
core   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

open access: yesAdvanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez   +8 more
wiley   +1 more source

Notas sobre la nidificación del Chopí (Gnorimopsar chopi) en Argentina y Paraguay, con datos de cría cooperativa y de parasitismo de cría por el Tordo Pico Corto (Molothrus rufoaxillaris) [PDF]

open access: yes, 2008
Fil: Fraga, Rosendo Manuel. Provincia de Entre Ríos. Centro de Investigaciones Científicas y Transferencia de Tecnología a la Producción. Universidad Autónoma de Entre Ríos.
Fraga, Rosendo Manuel
core  

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