Results 51 to 60 of about 1,755 (115)

Mapping Functionally Relevant Tractable Lysines of Challenging Protein Targets by Covalent Fragment Screening

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Screening a lysine‐targeting covalent fragment library against challenging protein targets revealed suitable warheads and characterized binding sites for the development of targeted covalent ligands. Covalent fragment screening has become an established strategy for identifying targetable amino acid residues or viable chemical starting points against ...
Noémi Csorba, Péter Ábrányi‐Balogh, Zoltán Orgován, Tibor Viktor Szalai, György G. Ferenczy, Levente Kollár, Nikolett Péczka, Tímea Imre, József Simon, Pál Szabó, Gitta Schlosser, Martina Hrast, Stanislav Gobec, Varbina Ivanova, Carles Galdeano, Aleksandra Kopranovic, Marc Neumann, Franz‐Josef Meyer‐Almes, György Miklós Keserű   +18 more
wiley   +1 more source

Serviços Farmacêuticos em Hospitais

Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde, 2019
O Ministério da Saúde, no final de 2010, publicou a Portaria 4283/10, apresentado à sociedade diretrizes e estratégias para organização, fortalecimento e aprimoramento das ações e serviços de farmácia no âmbito dos hospitais.
Marco Aurélio Pereira, , José Miguel do Nascimento Júnior2   +1 more
doaj  

Molecular Insights and Repellent Efficacy of the Essential Oil and Major Compounds From Piper cyrtopodon (Miq.) C.DC (Piperaceae) Against Aedes aegypti (Linnaeus, 1762) (Culicidae)

Archiv der Pharmazie, Volume 359, Issue 6, June 2026.
The essential oil and major compounds from Piper cyrtopodon exhibit potent, long‐lasting repellent activity against Aedes aegypti mosquitoes, combined with low cytotoxicity and favorable molecular docking interactions with odorant‐binding proteins. These findings highlight its potential for the development of alternative products for bite prevention ...
Maria L. L. da Costa, Renata G. de Azevedo, Sergio M. Nunomura, Rita de C. S. Nunomura, Gemilson S. Pontes, Rosemary A. Roque, Tatiane P. de Souza, André C. de Oliveira   +7 more
wiley   +1 more source

La muerte de la clínica y el malestar del médico

Revistas Argentina de Medicina, 2016
El paradigma dominante de atención médica basado en su mercantilización ha modificado profundamente el trabajo médico. La introducción del aseguramiento, público o privado, como mecanismo de financiamiento y de la competencia entre administradores de ...
Asa Critina Laurell
doaj   +2 more sources

Validation and Application of an HPLC–UV Method for the Quantification of 3‐O‐Methylquercetin in Nasal Mucosa

ELECTROPHORESIS, Volume 47, Issue 6, Page 479-488, June 2026.
This study improved an HPLC–UV method for quantifying 3‐O‐methylquercetin in porcine nasal mucosa following ICH M10 and ANVISA (Brazil) guidelines, assessing selectivity, linearity, accuracy, precision, and robustness. The method was applied for the first time to evaluate release, permeation, and retention profiles of a nasal formulation.
Jeniffer Viviana Ramirez Hernández, Laura da Silva Machado, Flávia Nathiely Silveira Fachel, Sara Elis Bianchi, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +6 more
wiley   +1 more source

Tableta masticable de lecitina de soya: de subproducto a producto farmacéutico

Medisan, 2017
En el Laboratorio Farmacéutico “Oriente” de Santiago de Cuba se acometió el desarrollo de una tableta masticable de lecitina de soya con fines de registro y ulterior producción, lo cual se realizó durante el bienio 2011-2013. Se utilizaron excipientes de
Martha Zoe Lemus Rodríguez, Amaury Chong Quesada, Jorge Bosch Escobar   +2 more
doaj  

Prescrição eletrônica como instrumento de qualificação da assistência farmacêutica no Brasil

Jornal de Assistência Farmacêutica e Farmacoeconomia
A prescrição eletrônica é uma inovação tecnológica que visa aprimorar a qualidade da Assistência Farmacêutica. Permite que profissionais de saúde prescrevam medicamentos em um registro eletrônico, contendo campos e dados estruturados e interoperáveis ...
Joselio Queiroz, Elivan Silva Souza , Gabriella Nunes Neves, Paula Xavier dos Santos , Paula Luedy Mendes, Robson Willian de Melo Matos, Rafael Santos Santana   +6 more
doaj   +1 more source

Quinoa Protein Concentrate as a Platform for the Protection and Controlled Delivery of Resveratrol and Tocopherol

Sustainable Food Proteins, Volume 4, Issue 2, June 2026.
Graphical abstract illustrating the development of quinoa protein (QP) nanocarriers for the encapsulation of resveratrol (RSV) and tocopherol (TOC). ABSTRACT The objective of this work was to generate and characterize complexes of quinoa proteins (QP) with either resveratrol (RSV) or tocopherol (TOC) whose dimensions fell into the nanoscale.
Alejandra J. Rubinstein, Guadalupe Garcia Liñares, Valeria Boeris, Oscar E. Pérez   +3 more
wiley   +1 more source

Mild and Metal‐Free CH Arylation of Imidazoles via In Situ Diazotization in Water

Advanced Synthesis &Catalysis, Volume 368, Issue 10, 19 May 2026.
Imidazoles undergo direct C–H arylation through in situ generated diazonium salts in water, under ambient and catalyst‐free conditions. This operationally simple method avoids hazardous intermediates, tolerates sensitive functional groups, and preserves C–halogen bonds.
Elisabetta Rosadoni, Zefiro Ferraro Fano, Angela Rosa Cuzzola, Fabio Bellina   +3 more
wiley   +1 more source

RECURSOS BIOLÓGICOS AMAZÔNICOS: PESQUISAS E PATENTES SOBRE PLANTAS MEDICINAIS DA AMAZÔNIA

Cadernos Prolam/USP, 2008
A partir da década de 80, com o desenvolvimento de novas técnicas de pesquisa e utilização dos recursos biológicos, as plantas passaram a ser objeto de estudos por parte da indústria, principalmente farmacêutica, na procura de novas substâncias com ...
Wagner Siloto Hoerner
doaj   +1 more source