Results 21 to 30 of about 39,315,652 (192)
Frontiers in Aging NeuroscienceIntroductionGait alterations have been proposed as functional indicators of neural dysfunction in Alzheimer's disease; however, their ability to capture disease-associated locomotor changes in preclinical models remains insufficiently characterized ...
Lidia Castillo Mariqueo +6 more
doaj +1 more source
Angewandte Chemie, EarlyView.Durch einen strukturbasierten Designansatz wurden photoschaltbare Derivate des von der FDA zugelassenen Arzneistoffes Suvorexant entwickelt, gedockt, synthetisiert und pharmakologisch an den Orexin‐1‐ und 2‐Rezeptoren (OX1R und OX2R) charakterisiert.
Marcus Angermann +10 more
wiley +1 more source
Revista Panamericana de Salud PúblicaObjetivo. Describir las actividades integrales implementadas en la República Bolivariana de Venezuela para la reverificación de la eliminación del sarampión en el 2023. Método.
Lesbia Muro +10 more
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann +10 more
wiley +1 more source
Behavioral patterns in elderly single-person households
HeliyonThe global rise in the aging population and the increase in older adults living alone have raised concerns about health-related behaviors, particularly sedentary lifestyles and reduced daily activities.
David Araya +3 more
doaj +1 more source
Animal Research and One Health, EarlyView.Intensive or organic farming systems may expose pigs to management or environmental challenges. Our preliminary results concluded that organic farming might enhance adaptive immune function, showing that improvements in welfare can translate into measurable immunological benefits, based on the correlation between welfare assessment and physiological ...
Dorotea Ippolito +15 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims This study aimed to evaluate the acute effects of cannabidiol plus tetrahydrocannabinol (CBD+THC) and tetrahydrocannabinol (THC) oils on cardiovascular haemodynamics, respiratory muscle activity and peripheral tissue perfusion in healthy adults. Methods In this randomized, double‐blind, crossover trial, participants received orally administered ...
Edna Karla Ferreira Laurentino +9 more
wiley +1 more source
The Canadian Journal of Chemical Engineering, EarlyView.Timeline of key academic milestones and individuals that shaped chemical engineering at FQ‐UNAM and in Mexico. Abstract One hundred years after the beginning of the teaching of Chemical Engineering in Mexico, which started in 1925 in the former National School of Chemical Sciences, currently Faculty of Chemistry (FQ) at National Autonomous University ...
Patricia Pérez‐Salinas +2 more
wiley +1 more source
Masividad, calidad y racionalidad de generación de recursos humanos en salud: Reflexiones iniciales para una política de ingreso a las Facultades de Medicina. [PDF]
, 2007 Un componente esencial de la respuesta de las sociedades frente al fenómeno de la masividad universitaria ha sido también la exigencia de evaluación de la calidad y muy probablemente, el desafío de masividad con calidad sea el gran desafío de la ...
Fió, Damián +3 more
core
Effects of different foods and cooking methods on the gut microbiota: an in vitro approach
Frontiers in MicrobiologyTo support personalized diets targeting the gut microbiota, we employed an in vitro digestion-fermentation model and 16S rRNA gene sequencing to analyze the microbiota growing on representative foods of the Mediterranean and Western diets, as well as the
Alberto M. Lerma-Aguilera +15 more
doaj +1 more source