Results 51 to 60 of about 5,792 (191)
The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes
The FEBS Journal, EarlyView.Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova +12 more
wiley +1 more source
Revista Facultad Nacional de Salud Pública, 2013 Los jóvenes se consideran un grupo poblacional relativamente sano, de ahí la necesidad de repensar el autocuidado como estrategia para promover su salud.
María del Pilar Escobar +1 more
doaj
On Integral Priors for Multiple Comparison in Bayesian Model Selection
International Statistical Review, EarlyView.Summary Noninformative priors constructed for estimation purposes are usually not appropriate for model selection and testing. The methodology of integral priors was developed to get prior distributions for Bayesian model selection when comparing two models, modifying initial improper reference priors. We propose a generalisation of this methodology to
Diego Salmerón +2 more
wiley +1 more source
Incident Lung Cancer and Mortality: Data From Health ABC Using Periodontal Status and Tooth Loss
Oral Diseases, EarlyView.ABSTRACT Aim To evaluate whether periodontal parameters and tooth loss are associated with lung cancer incidence and mortality among older adults. Materials and Methods Data are from the Health, Aging and Body Composition (Health ABC) study, which included 1136 older adults who received a periodontal examination and were followed for up to 16 years ...
Taciane Menezes da Silveira +5 more
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.ABSTRACT Background Compared to their healthy peers, children and adolescents with type 1 diabetes are at an increased risk of adverse changes in body composition, including increased fat mass along with reductions in lean and bone mass. Although exercise has shown promise in improving body mass index in this population, the individual effects of ...
Jacinto Muñoz‐Pardeza +6 more
wiley +1 more source
The Open Reading Frame 7b of the SARS‐CoV‐2 Disperse Trans‐Golgi and Activate the NLRP3 Inflammasome
Journal of Medical Virology, Volume 98, Issue 4, April 2026.ABSTRACT Inflammasomes orchestrate the inflammatory response against bacterial and viral infections, thereby initiating the synthesis of pro‐inflammatory cytokines, mainly IL‐1β and IL‐18. SARS‐CoV‐2 infection induces an inflammatory response mediated by the activation of NLRP1 and NLRP3 inflammasomes.
Julio García‐Villalba +4 more
wiley +1 more source
Toxicology ReportsExposure to environmental contaminants, particularly lead (Pb), has increased due to anthropogenic activities and has been associated with epigenetic alterations, including changes in microRNA (miRNA) expression.
Alejandra González-Bravo +8 more
doaj +1 more source
British Journal of Pharmacology, Volume 183, Issue 7, Page 1404-1426, April 2026.The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez +13 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, Volume 20, Issue 3, Page 850-862, March 2026.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
La alimentación preescolar, educación para la salud de los 2 a los 6 años
Enfermería Global, 2012 La alimentación y nutrición infantil constituye una de las áreas de mayor importancia dentro de la Educación para la Salud (EpS). Esta acción promotora de la salud debe iniciarse en la fase temprana del desarrollo y aprendizaje, como es la etapa ...
Javier Cubero Juánez +7 more
doaj +1 more source