Results 61 to 70 of about 179,142 (235)

Revista Tecnología en Marcha. Vol. 28-2. Abril-Junio 2015

Tecnología en Marcha, 2015
Revista Tecnología en marcha
doaj   +1 more source

Coelhos: tecnologia humana e tecnologia material

POIÉSIS, 2018
Este ensaio discute os conceitos de diagrama e de dispositivo a partir do debate entre Peter Eisenman e Rem Koolhaas, tentando pensá-los nas relações entre arquitetura e arquitetura conceitual.
openaire   +3 more sources

Direct Measurement of the Singlet Lifetime and Photoexcitation Behavior of the Boron Vacancy Center in Hexagonal Boron Nitride

Advanced Optical Materials, EarlyView.
Negatively charged boron vacancy defects in hexagonal boron nitride promise near‐surface quantum sensing, but their internal spin transition rates are only partly understood. This work directly measures the defect's singlet‐state lifetime, 15(3) ns, using a nanosecond rise‐time dual‐pulse photoluminescence‐recovery method, and shows that high laser ...
Richard A. Escalante, Andrew J. Beling, Daniel G. Ang, Niko R. Reed, Justin J. Welter, John W. Blanchard, Cecilia Campos, Edwin Coronel, Klaus Krambrock, Alexandre S. Leal, Paras N. Prasad, Ronald L. Walsworth   +11 more
wiley   +1 more source

Revista Tecnología en Marcha. Vol. 28-1. Enero-marzo 2015

Tecnología en Marcha, 2015
Revista Tecnología en marcha
doaj   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Revista Tecnología en Marcha. Vol. 27-4. Octubre-diciembre 2014

Tecnología en Marcha, 2014
Revista Tecnología en marcha
doaj   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Revista Tecnología en Marcha. Vol. 28-3. Julio-Setiembre 2015

Tecnología en Marcha, 2015
Revista Tecnología en marcha
doaj   +1 more source

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source

Número completo 27-2

Tecnología en Marcha, 2014
Revista Tecnología en marcha
doaj   +1 more source