Results 71 to 80 of about 74,013 (289)
Advanced Science, EarlyView.xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben +4 more
wiley +1 more source
Advanced Science, EarlyView.Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang +7 more
wiley +1 more source
Executive Functioning as a Predictor of Adverse Driving Outcomes in Teen Drivers With ADHD. [PDF]
J Atten Disord, 2023 Lynch JD +8 more
europepmc +1 more source
Children's Health Spending: 2010-2014 [PDF]
, 2016 Children's Health Spending: 2010-2014 examines spending on health care for children covered by employer-sponsored insurance from 2010 to 2014. For the first time, HCCI analyzed children's health care spending trends at the state level, reporting on ...
core
Advanced Science, EarlyView.This study delineates a novel HSP90AB1‐ITGBL1 signaling axis governing osteosarcoma. HSP90AB1 promotes K63‐linked ubiquitination and proteasomal degradation of ITGBL1. Restoring ITGBL1 induces reactive oxygen species‐dependent endoplasmic reticulum stress and pro‐death autophagy, suppressing tumor growth and metastasis.
Zhen Wang +17 more
wiley +1 more source
And If Your Friends Jumped Off A Bridge, Would You Do It Too? : How Developmental Neuroscience Can Inform Legal Regimes Governing Adolescents [PDF]
, 2015 Legal models of adolescent autonomy and responsibility in various domains of law span a spectrum from categorical prohibitions of certain behaviors to recognitions of total adolescent autonomy.
Pustilnik, Amanda C, Tennison, Michael N
core +1 more source
Advanced Science, EarlyView.Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu +6 more
wiley +1 more source
The Way Forward: From Sanctions to Supports [PDF]
, 2012 The New York City Working Group on School Transformation brought together education practitioners, school reformers, policy-makers, advocates, and parent and student leaders to propose alternatives to the school closings policy of the New York City ...
Barbara Gross +2 more
core
Advanced Science, EarlyView.This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
Drive Alive: Teen Seat Belt Survey Program
Western Journal of Emergency Medicine, 2010 Objective: To increase teen seat belt use among drivers at a rural high school by implementing the Drive Alive Pilot Program (DAPP), a theory-driven intervention built on highway safety best practices.Methods: The first component of the program was 20 ...
Loftin, Laurel +5 more
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