Results 171 to 180 of about 40,314 (264)
A multilevel analysis of trends and predictors associated with teenage pregnancy in Tanzania (2004-2022): evidence from demographic and health surveys. [PDF]
Stephano EE +3 more
europepmc +1 more source
Fibroblast Transcriptomics in Molecular Diagnostics of a Comprehensive Dystonia Cohort
Objective Genomic sequencing leaves >50% of dystonia‐affected individuals without a diagnosis. Where DNA‐oriented approaches remain insufficient, integrating multiomics is essential to advance genome interpretation. Herein, we incorporated RNA sequencing (RNA‐seq) data from 167 patients with dystonia across a range of ages and presentations. Methods We
Alice Saparov +42 more
wiley +1 more source
Listen to the Patient-She is Telling You the Diagnosis. [PDF]
Kannai R.
europepmc +1 more source
Objective Heightened sensitivity to noxious stimulation is a hallmark of chronic pain. Emerging evidence suggests heightened unpleasantness to non‐noxious (eg, auditory) aversive stimulation also characterizes chronic pain, but its magnitude, neural mechanisms, and treatment modifiability remain unknown.
Alina E. C. Panzel +4 more
wiley +1 more source
Teenage mothers report poor health and economic functioning in Western Kenya: A call to action. [PDF]
Jakubowski A +11 more
europepmc +1 more source
Objective Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first longitudinal natural history study of GNAO1‐related disorders (GNAO1‐RD) to delineate phenotypic trajectories. Methods Sixty‐six individuals
Jana Domínguez‐Carral +52 more
wiley +1 more source
Factors influencing contraceptive use among teenage girls in Ghana: analysis of the Ghana living standard survey 7. [PDF]
Aggrey-Korsah J +3 more
europepmc +1 more source
A Synergistic Inhibitor Development Strategy Against Human UDP‐Galactose‐4‐Epimerase
The epimerase GalE is crucial for the biosynthesis of cancer‐relevant O‐GalNAc glycans. Here, we employ orthogonal, structurally enabled small molecule fragment screens to yield both covalent and non‐covalent inhibitors against GalE within no more than 22 elaborated compounds.
William M. Browne +22 more
wiley +1 more source
Sociodemographic, Reproductive, and Clinical Profile of Patients With an Unhealthy Cervix: An Observational Study. [PDF]
Nene S, Dutta I, Kundu M.
europepmc +1 more source

