Results 61 to 70 of about 73,486 (308)
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Teenage childbearing and child health in Eritrea [PDF]
Data from the 2002 Eritrea Demographic and Health Survey (EDHS) are used to examine teenage childbearing and its health consequences. Bivariate analysis is used to calculate trends and differentials in teenage childbearing. Logistic and Cox hazard models
Gebremariam Woldemicael
core
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source
This article examines Mary Stolz’s Cold War adolescent girl romance novels—which I call “female junior novels”—to suggest that the dominant tropes that form the popular romance motifs within these texts (i. girls’ conformity, ii.
Amanda K. Allen
doaj
Background The end of active treatment is a period of high stress for young people with cancer, but limited literature exists about their information and support needs during this phase.
Sarah Lea +9 more
doaj +1 more source
The early socioeconomic effects of teenage childbearing [PDF]
A large body of literature has documented a negative correlation between teenage childbearing and teen mothers’ socioeconomic outcomes, yet researchers continue to disagree as to whether the association represents a true causal effect.
Dohoon Lee
core
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source

