Results 111 to 120 of about 440,167 (290)

HSP90AB1‐Mediated Ubiquitin‐Proteasome Degradation of ITGBL1 Promotes Osteosarcoma Progression by Inhibiting Endoplasmic Reticulum Stress‐Induced Autophagy

open access: yesAdvanced Science, EarlyView.
This study delineates a novel HSP90AB1‐ITGBL1 signaling axis governing osteosarcoma. HSP90AB1 promotes K63‐linked ubiquitination and proteasomal degradation of ITGBL1. Restoring ITGBL1 induces reactive oxygen species‐dependent endoplasmic reticulum stress and pro‐death autophagy, suppressing tumor growth and metastasis.
Zhen Wang   +17 more
wiley   +1 more source

Nature of individual difference in liability to depression in Russian adolescents [PDF]

open access: yesPsychology in Russia: State of Art, 2012
The Influence of genetic and environmental factors on liability to depression inRussian teenage sample was investigated. 196 twin pairs aged 13 to 17 (M=15,2)from Moscow, Izhevsk and Bishkek took part in the survey.
Sergey B. Malykh   +2 more
doaj  

Do teachers make better parents? -the differential performance of teachers’ children at school [PDF]

open access: yes
This paper investigates whether teenagers are educationally advantaged if their parents are educators, using PISA data for Great Britain and Ireland. It examines whether teachers’ children do better at tests of reading ability.
Kevin Denny
core  

AMISH TEENAGERS VIEWING THE WORLD IN A DOCUMENTARY FILM AMISH ON BREAK [PDF]

open access: yes, 2014
Agama telah menjadi ulasan menarik disetiap negara sejak dulu kala tak terkecuali di Amerika Serikat. Agama juga seolah sudah menjadi bagian penting di dalam kehidupan bermasyarakat dan berbudaya.
Purwaningsih, Siti
core   +1 more source

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity

open access: yesAdvanced Science, EarlyView.
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu   +6 more
wiley   +1 more source

Re-using features of English as a foreign language (EFL) materials for special needs students of the same age group [PDF]

open access: yes, 2006
This paper identifies a lack of age-appropriate literacy software for dyslexic teenagers in Irish classrooms and investigates the features of English as a Foreign Language (EFL) software that could be helpful to dyslexic students.
Greene, Cara N.
core  

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

open access: yesAdvanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao   +8 more
wiley   +1 more source

Teenagers' perspectives on the Canterbury earthquakes : an insight into their needs and experiences : a thesis presented in partial fulfillment of the requirements of the degree of Doctor of Clinical Psychology, Massey University, Wellington, New Zealand [PDF]

open access: yes, 2015
Natural disasters inflict physical, psychosocial, and economic impacts on individuals and their communities. Although a substantial number of disaster survivors are teenagers (13-19 years), this population group has not been widely investigated ...
Pine, Nicola Stacey
core  

Phenotypic Diversity and Outcomes in Pediatric NMDA Receptor Encephalitis: A 15‐Year Retrospective Study from the Largest Children's Hospital in the United States

open access: yesAdvanced Science, EarlyView.
ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss   +9 more
wiley   +1 more source

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