Results 251 to 260 of about 543,774 (351)

A Synergistic Inhibitor Development Strategy Against Human UDP‐Galactose‐4‐Epimerase

open access: yesAngewandte Chemie International Edition, EarlyView.
The epimerase GalE is crucial for the biosynthesis of cancer‐relevant O‐GalNAc glycans. Here, we employ orthogonal, structurally enabled small molecule fragment screens to yield both covalent and non‐covalent inhibitors against GalE within no more than 22 elaborated compounds.
William M. Browne   +22 more
wiley   +1 more source

Early warning model for depression and anxiety among adolescent students: an empirical study based on Guilin. [PDF]

open access: yesFront Public Health
Ma Q   +10 more
europepmc   +1 more source

Trabecular bone ontogeny of the human talus

open access: yesThe Anatomical Record, EarlyView.
Abstract Studies of trabecular ontogeny may provide insight into the factors that drive healthy bone development. There is a growing understanding of how the juvenile skeleton responds to these influences; however, gaps in our knowledge remain. This study aims to identify ontogenetic trabecular patterns and regional changes during development within ...
Rebecca A. G. Reid   +2 more
wiley   +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

open access: yesThe Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose   +2 more
wiley   +1 more source

Evaluation of Generative Artificial Intelligence Safeguards Against the Creation of Images and Videos Harmful to Public Health. [PDF]

open access: yesPublic Health Rep
Chu B   +11 more
europepmc   +1 more source

Cortical bone distribution in the human mandibular symphysis: Ontogenic and morphometric approaches in archeological context

open access: yesThe Anatomical Record, EarlyView.
Abstract The human mandibular symphysis concentrates multiaxial loads during function and remodels throughout growth, but the precise mechanisms underlying cortical bone shape during growth remain relatively unexplored. Approaches based solely on thickness or external cortical contours provide only partial insights and do not capture the functional ...
Ana Ribeiro   +3 more
wiley   +1 more source

Birth Rates Among Teenagers With Epilepsy in Michigan: A Retrospective Analysis of a Medicaid-Insured Cohort From 2016-2022. [PDF]

open access: yesPublic Health Rep
Alrubaie N   +6 more
europepmc   +1 more source

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