Results 181 to 190 of about 276,558 (254)

Genotype-directed Targeted Therapy for Pediatric Vascular Malformations: A Systematic Review. [PDF]

open access: yesJ Indian Assoc Pediatr Surg
Kumar B   +7 more
europepmc   +1 more source

Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li   +6 more
wiley   +1 more source

Modulation of the Receptor Tyrosine Kinase TIE2/<i>Tek</i> Pathway by NRF2 Activation in Neurovascular Endothelial Cells. [PDF]

open access: yesInt J Mol Sci
Cazalla E   +6 more
europepmc   +1 more source

Investigation of the laser fluence and wavelength dependence in surface‐assisted laser desorption/ionization mass spectrometry using gold nanoparticles

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
Rationale Surface‐assisted laser desorption/ionization (SALDI) mass spectrometry (MS) builds on the use of nanostructured surfaces (e.g., coatings of colloidal nanoparticles) to promote analyte desorption and ionization. The SALDI process is believed to occur mainly through thermal processes, resulting from heating of the nanosubstrate upon absorption ...
Wendy H. Müller   +3 more
wiley   +1 more source

Vascular basement membrane laminins modulate functional zonation of cerebral microvessels. [PDF]

open access: yesJ Cereb Blood Flow Metab
Deshpande T   +16 more
europepmc   +1 more source

Reconciling Granular Hydrogel Microstructure and Mechanics via a Temporary Thermo‐Responsive and Cell‐Invadable Matrix

open access: yesSmall, EarlyView.
Thermo‐responsive granular hydrogels (TRGHs), composed of microparticles and an interstitial matrix, exhibit thermo‐responsive mechanical properties and allow cell infiltration. This system effectively addresses the conventional compromise between mechanical strength and porosity observed in granular hydrogels.
Jun Kim, Soyeon Kwon, Taimoor H. Qazi
wiley   +1 more source

Quantitative Imaging of Human Hemoglobin Binding to Staphylococcus aureus With Single‐Molecule Resolution

open access: yesSmall, EarlyView.
Single‐molecule localization microscopy is exploited to quantify the number of hemoglobin copies bound to specific receptors on S. aureus wall. This quantification supports the design of a photoactive derivative of hemoglobin able to photo‐inactivate S.
Pietro Delcanale   +10 more
wiley   +1 more source

Kirigami‐Inspired Deployable Microneedle Robot With Enhanced Conformability for Targeted Oral Drug Delivery

open access: yesSmall, EarlyView.
We have engineered a kirigami‐inspired deployable microneedle robot (KiriBot) capable of remotely controlled attachment to target tissues for sustained drug release. KiriBot incorporates a flexible structure that enhances conformability, improves adherence to irregular tissues, and facilitates microneedle insertion.
Kun Zhou   +11 more
wiley   +1 more source

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