Results 231 to 240 of about 390,603 (312)

Reducing risk for chronic disease: evaluation of a collective community approach to sustainable evidence-based health programming. [PDF]

BMC Public Health
Oestman K, Rechis R, Williams PA, Brown JA, Treiman K, Zulkiewicz B, Walsh MT, Basen-Engquist K, Rodriguez T, Chennisi C, Macneish A, Neff A, Pomeroy M, Bhojani FA, Hawk E.   +14 more
europepmc   +1 more source

Bioinspired, Guanidinium, and Indole Modified Poly(glycidyl ether)s as Highly Efficient Vectors for Polyplex‐Mediated Gene Delivery

Macromolecular Rapid Communications, EarlyView.
Guanidinium‐ and indole‐functionalized poly(glycidyl ether)s were developed as non‐viral gene delivery vectors with tunable hydrophilic–hydrophobic balance. All polymers formed stable DNA polyplexes, while moderate indole content yielded the highest transfection efficiency at low N/P ratios.
Markus Kötzsche, Andreas Dzierza, Lennert Sölter, Jan Egger, Kjell Cornelis, Andreas Stihl, Felix H. Schacher, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Systematic Deciphering of ATBC Nephrotoxicity Mechanisms via Machine Learning and Single‐Cell Analysis

Medicine Bulletin, EarlyView.
This study elucidates the nephrotoxic mechanism of acetyl tributyl citrate (ATBC) by integrating network toxicology, machine learning, and single‑cell multi‑omics analysis to systematically decipher the molecular mechanisms and cell‑type‑specific regulatory networks underlying ATBC‑induced kidney injury. First, a protein‑protein interaction network was
Yimao Wu, Yalun Liang, Jintao Liang, Wenlong Sun, Qian Zhang, Meng‐Yao Li   +5 more
wiley   +1 more source

Who is local and what do they know? Braiding knowledges within carnivore management in Europe

People and Nature, EarlyView.
Abstract Growing recognition of Indigenous Peoples and traditional local communities as stewards of biodiversity has brought to the fore the issues of knowledge and value pluralism in conservation policy and practice. Given their basis in practical and multi‐generational experience, Indigenous and local knowledges are highly relevant to managing human ...
Hanna Pettersson, Lou Lécuyer, Juliette Young, Lindsay Stringer, Simon Calla, Erika Juhász, Zsolt Molnár   +6 more
wiley   +1 more source

Truncated FOS impairs osteogenic differentiation and induces prostaglandin and NFκB signalling in an in vitro cell‐of‐origin model for osteoid osteoma and osteoblastoma

The Journal of Pathology, EarlyView.
Abstract Osteoid osteoma and osteoblastoma are non‐malignant bone‐forming tumours of the skeleton, characterised by the presence of irregular trabeculae of woven bone. Rearrangements in FOS, and less frequently FOSB, have recently been identified in osteoid osteoma and osteoblastoma.
Suk Wai Lam, Tatiana Belova, Natasja Franceschini, Brendy van den Akker, David GP van IJzendoorn, Harald MM Mikkers, Hailiang Mei, Anne‐Marie Cleton‐Jansen, Marieke L Kuijjer, Karoly Szuhai, Judith VMG Bovée   +10 more
wiley   +1 more source

PTQ10‐based organic photodetectors for visible light detection and their tolerance to impurities

Polymer International, EarlyView.
PTQ10‐based organic photodetectors were found to be very sensitive to the presence of Pd(PPh3)4 catalyst traces, impacting the transport properties and light detection capacities. Abstract PTQ10 donor polymer has attracted a lot of interest in organic optoelectronics, particularly in the field of organic photovoltaics, owing to its ease of synthesis ...
Chloé Dindault, Gilles Henri Roche, Martial Leyney, Tanguy Jousselin‐Oba, Laurence Vignau, Sylvain Chambon, Pierre‐Antoine Bonnardel, Sébastien Taillemite, Guillaume Wantz, Lionel Hirsch   +9 more
wiley   +1 more source

A comprehensive checklist of Mediterranean wild edible plants: Diversity, traditional uses, and knowledge gaps

PLANTS, PEOPLE, PLANET, EarlyView.
The use of wild edible plants and the traditional knowledge associated with them are rapidly disappearing across the Mediterranean, with serious consequences for biodiversity, cultural heritage, and regional food security. This study compiles and organizes fragmented information to create the first comprehensive catalogue of these plants across the ...
Benedetta Gori, Tiziana Cossu, Hicham El Zein, Udayangani Liu, Tiziana Ulian, Gianluigi Bacchetta   +5 more
wiley   +1 more source

Conservation status of species used in the UK herbal medicine industry

PLANTS, PEOPLE, PLANET, EarlyView.
Given the ongoing biodiversity crisis, sustainable use and management of medicinal plants is critical. We assessed the conservation status, threats and conservation actions of 298 species sold by UK suppliers to medical herbalists. We found that most species used are unevaluated, representing a gap in conservation knowledge, and of those with ...
Isabella Flowers, Jon C. Lovett, Christopher Hassall   +2 more
wiley   +1 more source

Sensitivity of Irish Pyrenopeziza brassicae populations to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides

Pest Management Science, EarlyView.
For three collections of Irish Pyrenopeziza brassicae populations fungicide sensitivity status to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides was determined using sensitivity screening in vitro. Molecular mechanisms of insensitivity have been identified for MBC and QoI in
Diana E Bucur, Yong‐Ju Huang, Bruce DL Fitt, Steven Kildea   +3 more
wiley   +1 more source