Results 261 to 270 of about 394,251 (311)

Unexpected Promotion of Bone Regeneration by Inhibition of BMPR1A‐Mediated BMP Signalling

Cell Proliferation, EarlyView.
BMPR1A downregulation reduces ID1, releases TCF3 to activate GNG4‐PI3K‐AKT signalling, thereby promoting OPC proliferation and bone regeneration. ABSTRACT Bone morphogenetic protein (BMP) signalling plays a pivotal role in bone regeneration by regulating osteoprogenitor cell (OPC) function, and BMPs have been widely used in clinical treatment. However,
Zihao Zhou, Yun Zhai, Xiaochen Liu, Jiaojiao Shao, Jiani Zhou, Zhaoyang Li, Jiale He, Shuxian Lin, Qi Zhang   +8 more
wiley   +1 more source

Autoinflammatory patients with Golgi-trapped CDC42 exhibit intracellular trafficking defects leading to STING hyperactivation and ER stress. [PDF]

Nat Commun
Iannuzzo A, Delafontaine S, El Masri R, Tacine R, Prencipe G, Nishitani-Isa M, van Wijck RTA, Bhuyan F, de Jesus Rasheed AA, Coppola S, van Daele PLA, Insalaco A, Goldbach-Mansky R, Yasumi T, Tartaglia M, Meyts I, Delon J.   +16 more
europepmc   +1 more source

Toward a more inclusive conservation actions classification: Lessons from restoration practice and conservation social science

Conservation Science and Practice, EarlyView.
The Open Standards for the Practice of Conservation and the associated Conservation Actions Classification 2.0 serve as important and widely used tools to plan, implement, and monitor projects. Drawing a research effort that used the CAC 2.0 as a classification tool to synthesize the Great Lakes Restoration Initiative's thousands of projects, this ...
Matthew Jurjonas
wiley   +1 more source

Oral Angiolymphoid Hyperplasia With Eosinophilia Exhibiting Cutaneous‐Type Histopathologic Features: Clinical Regression Following Hormonal Withdrawal and a 50‐Year Review

Journal of Cutaneous Pathology, EarlyView.
Case report of a 30‐year‐old female. Asymptomatic, red‐purple hyperplastic lesion extending from teeth 21 to 25, with bleeding upon manipulation. Differential diagnosis included: inflammatory gingival hyperplasia, plasma cell gingivitis, leukemia, and Wegener's granulomatosis.
Pedro Vinícius Santos de Jesus, Louise Cristina Santos, Gilberth Tadeu Dos Santos Aciole, John Lennon Silva Cunha, Nicole Lonni, Matheus Antoni da Silva Costa, Elena Riet Correa Rivero, Rogério Gondak, Ricardo Luíz Cavalcanti de Albuquerque‐Júnior   +8 more
wiley   +1 more source

Effects of glial-derived neurotrophic factor on remodeling and mitochondrial function in human airway smooth muscle cells.

Am J Physiol Lung Cell Mol Physiol
Drake LY, Roos BB, Teske JJ, Borkar NA, Ayyalasomayajula S, Klapperich C, Koloko Ngassie ML, Pabelick CM, Prakash YS.   +8 more
europepmc   +1 more source

Predicting Historical Populations and Evaluating Shifting Baselines of Traditionally Exploited Fisheries

Fish and Fisheries, EarlyView.
ABSTRACT Development of data‐intensive stock assessment and ecosystem‐based models has improved our understanding of shifting species abundance in response to fishing, ocean ecology, and species interactions. Along with this analytical progress is evidence that many stocks lack data required for complex models, resulting in data‐limited options for ...
Allegra Ervin, Robert M. Cerrato, Adrian Jordaan, Michael G. Frisk   +3 more
wiley   +1 more source

Ist2 promotes lipid transfer by Osh6 via its membrane tethering and lipid scramblase activities. [PDF]

Sci Adv
Fabbre A, Syska C, Sebinelli HG, Cardinal A, Magdeleine M, Al-Qatabi N, D'Ambrosio JM, Montigny C, Lenoir G, Čopič A, Drin G.   +10 more
europepmc   +1 more source

Role of STIM1 in stretch-induced signaling in human airway smooth muscle.

Am J Physiol Lung Cell Mol Physiol
Yao Y, Zheng M, Borkar NA, Thompson MA, Zhang EY, Koloko Ngassie ML, Wang S, Pabelick CM, Vogel ER, Prakash YS.   +9 more
europepmc   +1 more source

NX210c drug candidate peptide strengthens mouse and human blood-brain barriers. [PDF]

Fluids Barriers CNS
Greene C, Rebergue N, Fewell G, Janigro D, Godfrin Y, Campbell M, Lemarchant S.   +6 more
europepmc   +1 more source