Results 161 to 170 of about 30,832 (224)

Focused Ultrasound for Essential Tremor in Denmark: Results After 1 Year of Follow‐Up

open access: yesMovement Disorders, EarlyView.
Abstract Background Essential tremor (ET) is the most common hyperkinetic movement disorder. Magnetic resonance‐guided focused ultrasound thalamotomy (MRgFUSTh) has become an established therapy in drug‐refractory tremor as one treatment option. Here, we present the results of a large cohort of MRgFUSTh‐treated ET patients followed‐up 1 year post ...
Victor Hvingelby   +33 more
wiley   +1 more source

Molecular Glue Degraders in Early Development for Cancer Therapy

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Molecular glue degraders are an emerging class of small molecule allosteric modulators that induce or stabilize protein‐protein interactions, enabling targeted degradation of previously intractable proteins. By redirecting E3 ligases to recognize neosubstrates, proteins that are not typically recognized by a specific E3 ubiquitin ligase, they ...
E. Sila Ozdemir   +4 more
wiley   +1 more source

A Modular Hybrid Framework for CEST MRI Development and Clinical Translation Using pTx‐Pulseq Preparation With Open‐ and Closed‐Source Readouts and ONNX Mapping

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Chemical exchange saturation transfer (CEST) MRI offers unique metabolic insights for imaging of cancer, stroke, or neurodegeneration. However, the rapid expansion of CEST preparation schemes and evaluation techniques creates a bottleneck; novel methods often remain complex prototypes requiring offline processing, preventing clinical ...
Martin Freudensprung   +9 more
wiley   +1 more source

Characterization of a Ten-Cysteine Peptide from Scorpion That Inhibits Classical Complement Activation via C4/C4b. [PDF]

open access: yesBiomolecules
Luo X   +11 more
europepmc   +1 more source

Leveraging Public Transit for Robotic Deliveries: A Column Generation Approach

open access: yesNaval Research Logistics (NRL), EarlyView.
ABSTRACT Autonomous mobile robots (AMRs) are small, electric, wheeled vehicles that operate at pedestrian speeds. In the last‐mile delivery service considered in this study, a fleet of AMRs is deployed across multiple recharging depots within a service area, from which they depart to perform point‐to‐point deliveries. We consider an operational setting
Yishay Shapira, Mor Kaspi
wiley   +1 more source

Bell's Palsy in 11,255 Cases: Cardiometabolic Associations in a Population‐Based Healthcare Database

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To estimate Bell's palsy incidence and evaluate the prevalence and associations with diabetes and other cardiometabolic conditions. Study Design Population‐based cohort study. Setting Clalit Health Services, the largest healthcare provider organization in Israel (2005‐2022).
Tomer Boldes   +5 more
wiley   +1 more source

Area‐restricted search under realistic constraints

open access: yesOikos, EarlyView.
Abstract Area‐restricted search (ARS) is one of the most influential and widely used concepts in foraging theory, capturing a simple rule by which animals intensify local search following a resource encounter. Because ARS performs well in many spatially structured environments, it serves as a basic model for interpreting movement patterns across taxa ...
Inon Scharf, Arik Dorfman
wiley   +1 more source

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