Results 211 to 220 of about 99,459 (305)

Normal Numbers of Stem Cell Memory T Cells Despite Strongly Reduced Naive T Cells Support Intact Memory T Cell Compartment in Ataxia Telangiectasia

open access: gold, 2021
Thomas J. Weitering   +5 more
openalex   +1 more source

Rapamycin Exerts Its Geroprotective Effects in the Ageing Human Immune System by Enhancing Resilience Against DNA Damage

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Using in vitro DNA damage assays in human T cells, ex vivo profiling of aged immune subsets and a small placebo‐controlled in vivo study, authors show that low‐dose rapamycin, a potent life‐extending mTOR inhibitor, enhances resilience against DNA damage in the human immune system.
Loren Kell   +8 more
wiley   +1 more source

Rosacea: Practical Guidance and Challenges for Clinical Management

open access: yesClinical, Cosmetic and Investigational Dermatology
Cassidy Nguyen,1,* Guilherme Kuceki,1,* Michael Birdsall,1 Dev Ram Sahni,2,3 Vikram Nath Sahni,2 Christopher M Hull2 1School of Medicine, University of Utah, Salt Lake City, UT, USA; 2Department of Dermatology, University of Utah Health, Salt ...
Nguyen C   +5 more
doaj  

Long‐term outcome of Coats' disease: Implications for the classification of foveal vascular pathologies

open access: yesActa Ophthalmologica, Volume 104, Issue 1, Page e104-e111, February 2026.
Abstract Purpose To investigate the long‐term outcome in patients with Coats' disease regarding initial stages. Methods Within a retrospective, clinical, single centre study, patients with diagnosed Coats' disease treated from 1992 to 2019 (minimum follow‐up of 12 months) were investigated. A total of, 75 out of 123 patients met the inclusion criteria.
Claudia Brockmann   +5 more
wiley   +1 more source

Capillary Telangiectasia [PDF]

open access: bronze
Ehab Harahsheh, Justin Cramer
openalex   +1 more source

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

open access: yesCancer Science, Volume 117, Issue 2, Page 297-307, February 2026.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki   +3 more
wiley   +1 more source

Avascular Necrosis and Minimal Trauma Fractures in Telomere Biology Disorders

open access: yesClinical Genetics, Volume 109, Issue 2, Page 286-293, February 2026.
Avascular Necrosis (AVN) and Minimal Trauma Fractures (MTF) cause significant morbidity in people with Telomere Biology Disorders (TBDs). They occur more frequently in young patients and in those with autosomal recessive (AR) or X‐linked recessive (XLR) than in autosomal dominant (AD) genotypes.
Arman M. Niknafs   +3 more
wiley   +1 more source

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