Results 31 to 40 of about 30,689 (265)

Peculiar Expression of CD3-Epsilon in Kidney of Ginbuna Crucian Carp

open access: yesFrontiers in Immunology, 2018
TCR/CD3 complex is composed of the disulfide-linked TCR-αβ heterodimer that recognizes the antigen as a peptide presented by the MHC, and non-covalently paired CD3γε- and δε-chains together with disulfide-linked ζ-chain homodimers.
Ryuichiro Miyazawa   +5 more
doaj   +1 more source

A Poorly Known Catfish Clade in an Endangered Neotropical Biodiversity Hotspot: Relationships and Distribution Patterns of the Cambeva variegata Group (Siluriformes: Trichomycteridae)

open access: yesFishes
The Cambeva variegata group (CVG) is endemic to a region situated in the intersection of two endangered biodiversity hotspots, Cerrado and Atlantic Forest, and drained by two important South American river basins, the upper Rio Paraná and upper Rio São ...
Wilson J. E. M. Costa   +7 more
doaj   +1 more source

Raptor/mTORC1 Acts as a Modulatory Center to Regulate Anti-bacterial Immune Response in Rockfish

open access: yesFrontiers in Immunology, 2019
The mammalian target of rapamycin (mTOR) is an evolutionarily highly conserved atypical serine/threonine protein kinase, which regulates cell growth, proliferation, apoptosis, autophagy, and metabolism.
Kang Li   +8 more
doaj   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

open access: yesAdvanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang   +20 more
wiley   +1 more source

Revisiting the Teleost Thymus: Current Knowledge and Future Perspectives

open access: yesBiology, 2020
The thymus in vertebrates plays a critical role in producing functionally competent T-lymphocytes. Phylogenetically, the thymus emerges early during evolution in jawed cartilaginous fish, and it is usually a bilateral organ placed subcutaneously at the ...
Felipe Barraza   +10 more
doaj   +1 more source

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

open access: yesAdvanced Science, EarlyView.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu   +11 more
wiley   +1 more source

Application of ovarian insemination method for the artificial reproduction of Caspian kutum (Rutilus frisii) under controlled conditions

open access: yesAquaculture Reports
The present study aims to compare the efficacy of the ovarian insemination technique with the traditional hormonal induction and artificial fertilization methods over the controlled reproduction of the Caspian kutum (Rutilus frisii).
Erfan Akbari Nargesi   +2 more
doaj   +1 more source

Draft Genome Assembly of the Freshwater Apex Predator Wels Catfish (Silurus glanis) Using Linked-Read Sequencing

open access: yesG3: Genes, Genomes, Genetics, 2020
The wels catfish (Silurus glanis) is one of the largest freshwater fish species in the world. This top predator plays a key role in ecosystem stability, and represents an iconic trophy-fish for recreational fishermen. S.
Mikhail Yu. Ozerov   +4 more
doaj   +1 more source

Exploration of GES-induced masculinization of Gambusia affinis Based on Single Cell Level

open access: yesGuangdong nongye kexue, 2023
【Objective】To investigate the molecular mechanism of sex reversal in female Western mosquitofish (Gambusia affinis) under the effect of gestodene (GES) by studying the development of gonadal cell differentiation and gene expression changes involved in ...
Tingyin FENG, Xikai DENG, Ke XING
doaj   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

open access: yesAdvanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang   +6 more
wiley   +1 more source

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