Results 91 to 100 of about 474,386 (339)

Generation of Sparse Antennas and Scatterers Based on Optimal Current Grid Approximation

open access: yesAlgorithms
The reduction in mass and surface of antennas and scattering structures is an important task in designing electromagnetic devices. To solve this task, we present a novel algorithm based on the optimal current grid approximation for generating sparse ...
Tuan Phuong Dang   +3 more
doaj   +1 more source

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

open access: yesAdvanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim   +11 more
wiley   +1 more source

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu   +12 more
wiley   +1 more source

Determining factors of university students' binge-watching attitudes

open access: yesHeliyon
Binge-watching (BW), defined as watching multiple episodes of a series or program in a single sitting, is recognized as a new and widespread form of viewing, especially with online streaming services.
Murat Aytas, Ismail Berkay Topatan
doaj   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

open access: yesAdvanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang   +9 more
wiley   +1 more source

Explicit Compression Degradation Estimations for Low‐Sampling Single‐Pixel Imaging using Hadamard Basis

open access: yesAdvanced Science, EarlyView.
This study proposes a degradation estimation technique to explicitly describe compressive sampling for low‐sampling Hadamard single‐pixel imaging. Blur kernels in explicit degradation models are estimated by the self‐supervised learning method without labeled data and implicit priors.
Haoyu Zhang   +4 more
wiley   +1 more source

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

open access: yesAdvanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang   +7 more
wiley   +1 more source

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