Results 161 to 170 of about 833,499 (300)

Valence ratings of recorded media for adults with and without hearing loss. [PDF]

open access: yesInt J Audiol
Huang H   +6 more
europepmc   +1 more source

No Significant Difference in Cost or Outcomes at 1‐Year Minimum Follow‐Up After Arthroscopic Partial Meniscectomy Comparing 1.9 mm Distal Chip‐on‐Tip Needlescope Versus 4 mm Glass Rod Lens Arthroscope: Both Treatments Are Highly Cost‐Effective

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate cost, outcomes, and incremental cost‐effectiveness of arthroscopic partial meniscectomy comparing visualization using a 1.9 mm distal chip‐on‐tip needlescope versus a standard 4 mm glass rod lens arthroscope. Methods We retrospectively reviewed prospectively collected data (from a larger randomized controlled trial) on patients ...
James H. Lubowitz, Chad Lavender
wiley   +1 more source

Is Chronotype Related to Eating Distractions Among Adolescents? The EHDLA Study. [PDF]

open access: yesNutrients
Masache-Cruz MJ   +9 more
europepmc   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

open access: yesArthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat   +14 more
wiley   +1 more source

Impact of Dual Interleukin‐17A and Interleukin‐17F Inhibition with Bimekizumab on Inflammatory and Structural Lesions in Axial Spondyloarthritis: MRI and Radiographic Outcomes from the Phase 3 BE MOBILE 1 and 2 Studies and their Open‐Label Extension

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives To evaluate the impact of bimekizumab, a dual IL‐17A and IL‐17F inhibitor, on sacroiliac joint (SIJ) and spine inflammation/structural damage in axSpA using MRIs/radiographs from the phase 3 studies BE MOBILE 1 (nr‐axSpA) and 2 (r‐axSpA) and their open‐label extension (OLE).
Walter P. Maksymowych   +10 more
wiley   +1 more source

MDL‐800‐induced SIRT6 activation decreases age‐associated osteoarthritis in mice

open access: yesArthritis &Rheumatology, Accepted Article.
Objective SIRT6 is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of a small molecule activator of SIRT6, MDL‐800, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez   +13 more
wiley   +1 more source

Dual Effects of β‐TrCP2 Deletion in Bone Homeostasis: Suppression of Osteoclastogenesis and Enhancement of Osteoblast Activity

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives To elucidate role of beta‐transducin repeat‐containing protein 2 (β‐TrCP2) in bone homeostasis for its potential as a therapeutic target for osteoporosis. Methods The role of β‐TrCP2 in bone phenotypes was investigated using systemic β‐TrCP1KO and β‐TrCP2KO mice, along with myeloid‐specific conditional β‐TrCP2KO (β‐TrCP2ΔM) mice.
Woo Jung Kim   +14 more
wiley   +1 more source

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