Results 191 to 200 of about 1,976,780 (394)

A pH‐Sensitive Nanosized Covalent–Organic Polymer for Enhanced Tumor Photodynamic Immunotherapy by Hypoxia Relief and STAT3 Inhibition

open access: yesAdvanced Science, EarlyView.
The nanosized covalent organic polymer composed of photosensitizer porphyrin, pyruvate kinase inhibitor vitamin K3, and STAT3 inhibitor WP1066 is prepared for enhanced photodynamic immunotherapy by simultaneous hypoxia relief and STAT3 inhibition. Abstract Photodynamic therapy (PDT) is a promising cancer therapy modality by generating reactive oxygen ...
Lei Lei   +7 more
wiley   +1 more source

Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

open access: yesAdvanced Science, EarlyView.
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye   +13 more
wiley   +1 more source

Television Viewing, Satisfaction and Happiness: Facts and Fiction [PDF]

open access: yes
Despite the increasing consumption of new media, watching television remains the most important leisure activity worldwide. Research on audience reactions has demostrated that there are major contradictions between television consumption and the ...
Luca Stanca, Marco Gui
core  

Lysosome‐Featured Cell Aggregate‐Released Extracellular Vesicles Regulate Iron Homeostasis and Alleviate Post‐Irradiation Endothelial Ferroptosis for Mandibular Regeneration

open access: yesAdvanced Science, EarlyView.
Lysosomal redistribution occurs via extracellular vesicles in multi‐stem cell aggregates and controls iron homeostasis for safeguarding cell aggregation. These cell aggregate‐released extracellular vesicles (CA‐EVs) rescue lysosomal impairments and exert anti‐ferroptosis effects in recipient irradiated endothelial cells.
Yuan‐Yuan Li   +20 more
wiley   +1 more source

Determining factors of university students' binge-watching attitudes

open access: yesHeliyon
Binge-watching (BW), defined as watching multiple episodes of a series or program in a single sitting, is recognized as a new and widespread form of viewing, especially with online streaming services.
Murat Aytas, Ismail Berkay Topatan
doaj  

What, when, and how food and beverage are advertised on Ghanian television. [PDF]

open access: yesPLoS One
Boncyk M   +8 more
europepmc   +1 more source

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