Results 61 to 70 of about 705,575 (301)
Advanced Science, EarlyView.A muscle‐bone endocrine pathway in aging is revealed in which extracellular vesicles released from atrophic skeletal muscle (Aged‐SKM‐EVs) inhibit bone formation. These EVs deliver miR‐125a‐5p to osteoblasts, thereby suppressing the SIRT7‐Sp7 signaling axis and osteogenic differentiation.
Xiaoyan Shao +22 more
wiley +1 more source
Technology Criticism in the Classroom (Chapter in The Nature of Technology)
, 2013 I first heard about a tragedy in Tucson, not from major television news networks, but from a direct message sent by a politically-active friend who was attending the political gathering where a mass shooting took place, including the shooting of an ...
Spencer, John
core
Archaeology in the Czech Media: Does anyone care?
Internet Archaeology, 2019 This article discusses the possibilities and effectiveness of the presentation of archaeological information and topics in Czech Television News in the context of continuing media convergence.
Zdeněk Šámal
doaj +1 more source
Advanced Science, EarlyView.This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño +5 more
wiley +1 more source
Advanced Science, EarlyView.A developmentally inspired osteochondral construct integrates mechanical and metabolic dual gradients within a 3D‐printed platform. Human MSC spheroids are spatially directed to form cartilage–bone interfaces, enabling evaluation of regeneration without biochemical reagents and assessment of drug responses. This physiologically relevant, phase‐specific
Yurim Choi +11 more
wiley +1 more source
How Chilean Editors Perceive and Define the Role of Melodrama in Television News
Palabra Clave, 2015 Several studies have addressed the role of drama and emotion in television news, oftentimes regarding them as opposed to quality journalism. Such approaches ignore the cultural resonance of melodramatic features in television newscasts in regions like ...
Constanza Mujica, Ingrid Bachmann
doaj
Advanced Science, EarlyView.SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding +10 more
wiley +1 more source
A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions
Advanced Science, EarlyView.This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies +14 more
wiley +1 more source
Capture, 2016 The focus of the research is to explore creativity in the application of linking techniquesto improve English fluency in order to increase the understanding of the English languagethrough the medium of television news.
Donie Fadjar Kurniawan
doaj +1 more source
Advanced Science, EarlyView.This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu +20 more
wiley +1 more source