Results 101 to 110 of about 113,241 (315)

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

open access: yesAdvanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen   +8 more
wiley   +1 more source

Converged digital TV services: The role of middleware and future directions of interactive television [PDF]

open access: yes, 2009
The subject of the future of the interactive Television medium has become a topic of great interest to the academic and industrial communities particularly since in recent years there has been a dramatic increase in the pace of innovation of convergence ...
Tsekleves, Emmanuel   +26 more
core   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

open access: yesAdvanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li   +9 more
wiley   +1 more source

Television, race and national identity : a study of South Africa's lifestyle programme Top billing

open access: yes, 2010
Includes bibliographical references (leaves 81-93).This thesis is an in-depth investigation into the weekly lifestyle/magazine programme Top Billing, aired on SABC3 (South African Broadcasting Corporation) – primarily in South Africa and in other ...
Jeon, Jin
core  

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

open access: yesAdvanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang   +6 more
wiley   +1 more source

The television work of Alfred Hitchcock [PDF]

open access: yes
The thesis uses close textual analysis to study and evaluate the television work of Alfred Hitchcock. The corpus consists of the twenty shows personally directed by Hitchcock, including his appearances before and after those shows.
Potts, Neill
core  

Memory Politics in Contemporary Russia : Television, Cinema and the State [PDF]

open access: yes, 2018
This book examines this societal dynamics of memory politics in Russia. Since Vladimir Putin became president, the Russian central government has increasingly actively employed cultural memory to claim political legitimacy and discredit all forms of ...
Mariëlle Wijermars   +1 more
core   +1 more source

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

open access: yesAdvanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu   +7 more
wiley   +1 more source

Researching Television Serial Narratives in Italy: an Overview

open access: yesSeries. International journal of tv serial narratives, 2015
In the essay the authors would like to review the main Italian studies that have focused on the television series, including both studies that have dealt with national production, and those which have looked to foreign markets and its serial products. In
Marta Martina, Attilio Palmieri
doaj   +1 more source

High‐Performance Prevascularized SHED‐Laden rGO@Hydrogel Achieves Optimized Diabetic Bone Defect Repair

open access: yesAdvanced Science, EarlyView.
A high‐performance 3D scaffold integrating rGO and SHEDs is developed to overcome impaired healing in diabetic bone defects. By driving extracellular matrix remodeling, rGO creates a pro‐angiogenic niche that significantly accelerates in vitro vascular network formation.
Can Zhang   +12 more
wiley   +1 more source

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