Results 101 to 110 of about 11,039,660 (346)
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
European Journal of Entomology, 2003 The cabbage armyworm, Mamestra brassicae, enters diapause in the early pupal stage. Pupal diapause is induced by rearing the larvae under short day lengths.
Masahide URYU +4 more
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Nature Communications, 2018 Understanding of ordered phases of interacting electrons in 2D systems is a fundamental many-body physics problem. Here, the authors report unconventional fractional quantum Hall phases in graphene Corbino devices originating from residual interactions ...
Manohar Kumar +2 more
doaj +1 more source
The Influence of the Carbonic Acid in the Air upon the Temperature of the Ground. Philosophical Magazine and Journal of Science, Vol. XLI La Revue Générale des Sciences. Svante Arrhenius [PDF]
, 1899 C. F. Tolman
openalex +1 more source
Conversations about weather, environment, health, cuisine, and even politics, all involve the word "temperature". It was an attempt to understand the working of heat engines that gave the temperature a clear definition. In this Note we put the equilibrium-thermodynamics definition into a larger context of the multiscale thermodynamics, the multiscale ...
openaire +2 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
ENTROPY CHANGES AT LOW TEMPERATURES. II. ETHYL AND PROPYL ALCOHOLS AND THEIR EQUAL MOLAL MIXTURE. [PDF]
, 1920 G. Gibson +2 more
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