Results 121 to 130 of about 18,522,447 (385)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

First-Principles Prediction of Doped Graphane as a High-Temperature Electron-Phonon Superconductor [PDF]

, 2010
G. Savini, Andrea C. Ferrari, Feliciano Giustino   +2 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Enhanced expression of genes in the brains of larvae of Mamestra brassicae (Lepidoptera: Noctuidae) exposed to short daylength or fed Dopa

European Journal of Entomology, 2003
The cabbage armyworm, Mamestra brassicae, enters diapause in the early pupal stage. Pupal diapause is induced by rearing the larvae under short day lengths.
Masahide URYU, Yohsuke NINOMIYA, Takeshi YOKOI, Seiji TSUZUKI, Yoichi HAYAKAWA   +4 more
doaj   +1 more source

Humboldt’s spa: microbial diversity is controlled by temperature in geothermal environments [PDF]

, 2014
Christine Sharp, Allyson L. Brady, Glen H Sharp, Stephen E. Grasby, Matthew B. Stott, Peter F. Dunfield   +5 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Low-temperature corrosion in large-scale biomass boilers

npj Materials Degradation
The shift toward biomass fuels for heat and power generation has introduced a range of new challenges for power plant technology, in particular large-scale boilers.
Farzad Jafarihonar, Emil Vainio, Leena Hupa, Mikko Hupa   +3 more
doaj   +1 more source

Elevated temperature crack growth [PDF]

, 1984
Critical gas turbine engine hot section components such as blades, vanes, and combustor liners tend to develop minute cracks during early stages of operations. The ability of currently available path-independent (P-I) integrals to correlate fatigue crack
Kim, K. S., Laflen, J. H., Vanstone, R. H., Yau, J. F.   +3 more
core   +1 more source

Quantum Nyquist Temperature Fluctuations

, 2002
We consider the temperature fluctuations of a small object. Classical fluctuations of the temperature have been considered for a long time. Using the Nyquist approach, we show that the temperature of an object fluctuates when in a thermal contact with a ...
A.V Balatsky, Callen, Chui, Cleland, Jian-Xin Zhu, Nyquist, Wilks   +6 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source