Results 121 to 130 of about 5,090,074 (298)

Highly effective energy transfer in the autotroph-heterotroph symbiosis: insights from compound-specific isotope analysis of amino acids

Progress in Earth and Planetary Science
Many species establish symbiotic partnerships with different organisms to benefit energetically from living together to fit into environments, and such symbiosis is frequently found in the modern ocean as well as throughout Earth’s history.
Jincen Li, Mio Shibuya, Yuko Takizawa, Yoshito Chikaraishi   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

High-Resolution Measurement of Air Temperatures and Temperature Differences [PDF]

, 1967
Donald W. Stevens
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Proposed standardized definitions for vertical resolution and uncertainty in the NDACC lidar ozone and temperature algorithms – Part 2: Ozone DIAL uncertainty budget

, 2016
Thierry Leblanc, R. J. Sica, J. A. E. van Gijsel, Sophie Godin‐Beekmann, Alexander Haefele, Thomas Trickl, Guillaume Payen, Gianluigi Liberti   +7 more
openalex   +1 more source

Simulating quantum vibronic dynamics at finite temperatures with many\n body wave functions at 0K [PDF]

, 2021
Angus Dunnett, Alex W. Chin
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Sterility caused by cooling treatment at the flowering stage in rice plants. I. The stage and organ susceptible to cool temperature.

, 1983
Tetsuo Satake, Setsuo Koike
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

How Flat is Flat? Investigating the spatial variability of snow surface temperature and roughness on landfast sea ice using UAVs in McMurdo Sound, Antarctica [PDF]

Julia Martin, Ruzica Dadić, Brian A. Anderson, Roberta Pirazzini, Oliver Wigmore, Lauren Vargo   +5 more
openalex   +1 more source