Results 151 to 160 of about 16,787,150 (404)
Global surface temperature has increased ≈0.2°C per decade in the past 30 years, similar to the warming rate predicted in the 1980s in initial global climate model simulations with transient greenhouse gas changes.
J. Hansen+5 more
semanticscholar +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
Desulfonema ishimotonii strain Tokyo 01T is a filamentous sulfate-reducing bacterium isolated from a marine sediment. In this study, the genome of this strain was sequenced and analyzed with a focus on gene transfer from phylogenetically distant ...
Miho Watanabe+4 more
doaj +1 more source
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy+12 more
wiley +1 more source
Publisher Correction: Nonlinear two-level dynamics of quantum time crystals
S. Autti+6 more
doaj +1 more source
Reciprocity relations between ordinary temperature and the Frieden-Soffer's Fisher-temperature
Frieden and Soffer conjectured some years ago the existence of a ``Fisher temperature" T_F that would play, with regards to Fisher's information measure I, the same role that the ordinary temperature T plays vis-a-vis Shannon's logarithmic measure.
A. Katz+7 more
core +1 more source
Can Temperature Be Quantized? [PDF]
It is shown that the temperature may be quantized in some spacetime due to the periodically topological structure of the Euclidean section. The quanta of the temperature is the Hawking-Unruh temperature.
arxiv
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
Understanding of ordered phases of interacting electrons in 2D systems is a fundamental many-body physics problem. Here, the authors report unconventional fractional quantum Hall phases in graphene Corbino devices originating from residual interactions ...
Manohar Kumar+2 more
doaj +1 more source