Results 151 to 160 of about 11,612,362 (357)

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

Unconventional fractional quantum Hall states and Wigner crystallization in suspended Corbino graphene

open access: yesNature Communications, 2018
Understanding of ordered phases of interacting electrons in 2D systems is a fundamental many-body physics problem. Here, the authors report unconventional fractional quantum Hall phases in graphene Corbino devices originating from residual interactions ...
Manohar Kumar   +2 more
doaj   +1 more source

Anisotropic Vortices in High-Temperature Superconductors and the Onset of Vortex-like Excitations above the Critical Temperature [PDF]

open access: yesarXiv, 2005
Recently we have found that a three-dimensional superconducting state with anisotropic vortices localized at the vortex-lattice points is a stable state in zero external magnetic field for the layered high temperature uperconductivity materials.
arxiv  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

TEMPERATURE OF THE CONJUNCTIVA [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1913
I. EARLIER METHODS OF MEASUREMENT Other students, appreciating the probable importance of this subject, have attempted similar measurements, but all of them were made with some modification of the mercurial thermometer. One form of this which attracted considerable attention was suggested by Galezowski.
openaire   +2 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Sensitivity adjustable in-line high-temperature sensor based on metal microwire optical Fabry-Perot interferometer [PDF]

open access: yesarXiv
The optical fiber Fabry-Perot interferometer (FPI) has been widely investigated as a potential temperature sensor. To function as a temperature sensor, the cavity of the FPI is typically constructed from either silica fibers or polymers. The silica cavity FPIs can function at temperatures exceeding 1000{\deg}C.
arxiv  

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

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