Results 191 to 200 of about 12,452,625 (335)

Impact of Various Sleeve Materials on Temperature Variations During Guided Endodontic Access Cavity Preparation Utilizing Finite-Element Analysis. [PDF]

Clin Exp Dent Res
Muryani A, Prasetia W, Aripin D, Dharsono HDA, Rajion ZA, Wicaksono S.   +5 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Nuclear relaxation in agar gel in the presence of highly concentrated PEG coated magnetic nanoparticles at low magnetic fields. Application of temperature dependent weighting for MRI thermometry. [PDF]

RSC Adv
Hankiewicz JH, Parigi G, Celinski ZJ, Hao Y, Angus AD, Petersen K, Lachowicz D, Kmita A, Przybylski M.   +8 more
europepmc   +1 more source

The effects of temperature and CO₂ enrichment on the red seaweed Asparagopsis taxiformis from Southern California with implications for aquaculture [PDF]

Hannah M. Resetarits, Gal Dishon, Vinayak Agarwal, Jennifer E. Smith   +3 more
openalex   +1 more source

Needle age and season influence photosynthetic temperature response and total annual carbon uptake in maturePicea marianatrees [PDF]

, 2015
Anna M. Jensen, J. M. Warren, Paul J. Hanson, Joanne Childs, Stan D. Wullschleger   +4 more
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Commercial fishing amplifies impacts of increasing temperature on predator-prey interactions in marine ecosystems. [PDF]

Nat Commun
Shurety AL, Thompson MSA, Couce E, Cameron TC, O'Gorman EJ.   +4 more
europepmc   +1 more source

Water Molecules in a Carbon Nanotube under an Applied Electric Field at Various Temperatures and Pressures [PDF]

, 2017
Winarto Winarto, Eiji Yamamoto, Kenji Yasuoka   +2 more
openalex   +1 more source

Anorthosite formation and emplacement coupled with differential tectonic exhumation of ultrahigh-temperature rocks in a Sveconorwegian continental back-arc setting

, 2022
Trond Slagstad, I.H.C. Henderson, Nick M.W. Roberts, Evgeniy Kulakov, Morgan Ganerød, Christopher L. Kirkland, Bjørgunn H. Dalslåen, Robert A. Creaser, Nolwenn Coint   +8 more
openalex   +1 more source