Results 31 to 40 of about 909,554 (261)

Analysis of heat transfer of variable conductance heat pipe for waste heat recovery of mine return air

open access: yesMeikuang Anquan, 2021
The variable conductance heat pipe(VCHP) is used to solve the problem of uncontrollable heat exchange of heat pipe for waste heat recovery of mine return air.
LU Yingzuo, BAO Lingling, LUO Jinghui, WANG Jinggang
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

DEVELOPMENT OF A PROBLEM-SOLVING-BASED E-MAGAZINE ASSISTED BY A VIRTUAL LABORATORY ON TEMPERATURE AND HEAT MATERIALS FOR SEVENTH GRADE JUNIOR HIGH SCHOOL STUDENTS

open access: yesJurnal Pendidikan Matematika dan IPA
This research aims to develop a problem-solving-based e-magazine learning media assisted by a virtual laboratory on temperature and heat material for grade VII junior high school students.
Auliasyura Lestari   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Development of 3D ELSA (3D E-Book Based on Scientific Literacy) on Temperature and Heat

open access: yesPrisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram, 2022
ELSA 3D (E-Book 3D Based on Scientific Literacy) is an e-book teaching material that integrates scientific literacy as a medium in the learning process on temperature and heat materials. This type of development research uses the Hannafin and Peck model.
Muhammad Zainal Arifin, Abd. Kholiq
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Developing and Validating a Web-Based Five-Tier DiagnosticInstrument to Identify Student Misconceptions on Temperature and Heat

open access: yesInternational Journal of Education and Teaching Zone
This study aims to develop and validate a web-based five-tier isomorphic diagnostic instrument to identify students’ misconceptions on temperature and heat concepts in junior high school.
Azizah Hanum, Maison, Yusnaidar
doaj   +1 more source

Investigation of flow and heat transfer of supercritical water in double-pipe heat exchanger

open access: yesZhongguo Jianchuan Yanjiu, 2021
ObjectiveThe flow and heat transfer of supercritical fluid is complex, and most of the existing research is based on the conditions of constant wall temperature and constant heat flux.
Lang LIU   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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