Results 71 to 80 of about 286,151 (306)

Retrieval of atmospheric water vapor and temperature profiles over Antarctica from satellite microwave observations using an iterative approach [PDF]

The Cryosphere
Retrieving atmospheric water vapor and temperature profiles over land using microwave radiometry is challenging due to uncertainties in estimating surface emissions.
Z. Zhang, S. Brown, A. Colliander
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Combining low- and high-frequency microwave radiometer measurements from the MOSAiC expedition for enhanced water vapour products [PDF]

Atmospheric Measurement Techniques
In the central Arctic, high-quality water vapour observations are sparse due to the low density of meteorological stations and uncertainties in satellite remote sensing.
A. Walbröl, H. J. Griesche, M. Mech, S. Crewell, K. Ebell   +4 more
doaj   +1 more source

Tropospheric water vapour and relative humidity profiles from lidar and microwave radiometry [PDF]

Atmospheric Measurement Techniques, 2014
In this paper, we outline an iterative method to calibrate the water vapour mixing ratio profiles retrieved from Raman lidar measurements. Simultaneous and co-located radiosonde data are used for this purpose and the calibration results obtained during a
F. Navas-Guzmán, J. Fernández-Gálvez, M. J. Granados-Muñoz, J. L. Guerrero-Rascado, J. A. Bravo-Aranda, L. Alados-Arboledas   +5 more
doaj   +1 more source

Average Path Profile of Atmospheric Temperature and Humidity Structure Parameters from a Microwave Profiling Radiometer [PDF]

Proceedings of The 1st International Electronic Conference on Atmospheric Sciences, 2016
The values of the key atmospheric turbulence parameters (structure constants) for temperature and water vapor, that is, C(exp 2)(sub T), and C(exp 2)(sub Q), are highly dependent upon the vertical height within the atmosphere thus making it necessary to specify profiles of these values along the atmospheric propagation path.
openaire   +1 more source

Effect of Temperature and Relative Humidity on Crop Yield in Tropical Greenhouse with Evaporative Cooling System [PDF]

, 2009
Tropical greenhouses require active evaporative cooling system such as pad-and-fan to ensure a suitable microclimate for crop production. Excess heat causes indoor temperature becoming hotter than desired resulting in detrimental effects to crop growth ...
Jamaludin, Diyana
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Sensitivity of thermodynamic profiles retrieved from ground-based microwave and infrared observations to additional input data from active remote sensing instruments and numerical weather prediction models [PDF]

Atmospheric Measurement Techniques
Accurate and continuous estimates of the thermodynamic structure of the lower atmosphere are highly beneficial to meteorological process understanding and its applications, such as weather forecasting.
L. Bianco, L. Bianco, B. Adler, B. Adler, L. Bariteau, I. V. Djalalova, I. V. Djalalova, T. Myers, T. Myers, S. Pezoa, S. Pezoa, D. D. Turner, J. M. Wilczak   +12 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source