Results 171 to 180 of about 5,511,418 (346)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Pharmacotherapeutic Controversies During Temperature Control After Out-of-Hospital Cardiac Arrest: A Semi-Structured Literature Review. [PDF]

Pharmacotherapy
Forehand CC, Benken ST, Madorsky M, Mohamed A, Nguyễn JV, Dixit D, Gallagher J, Hawkins WA, Heavner MS, Johnson E, Lozano L, Sisco M, Slampak-Cindric AA, Smith SE, Spezzano K, Taylor BA, Wayne NB, Gagnon DJ.   +17 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Development of a Rice Bread Baking Method via Gelatinization Temperature Control Using Modified Starch. [PDF]

J Appl Glycosci (1999)
Yano H, Murashita K, Sato R, Koda T, Nishioka A.   +4 more
europepmc   +1 more source

Temperature control after cardiac arrest. [PDF]

Resuscitation, 2023
Elmer J, Callaway CW.
europepmc   +1 more source

Temperature controller [PDF]

Metal Finishing, 2000
openaire   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Around the <i>ThermoClock</i>: A precision automated temperature control system for Ex Vivo circadian studies. [PDF]

MethodsX
Zhang KK, Locurto D, Belden M, Price M, Kearney CJ, Huber ME.   +5 more
europepmc   +1 more source

Effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute ischemic stroke PISA, a phase II double-blind, randomized, placebo-controlled trial [ISRCTN98608690] [PDF]

, 2003
Diederik W.J. Dippel, Eric van Breda, H. Bart van der Worp, H. Maarten A. van Gemert, Ron J. Meijer, L. Jaap Kappelle, Peter J. Koudstaal, the PISA-investigators.   +7 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source