Results 141 to 150 of about 14,157 (254)

Emergent cooperative superstructures via order-disorder kinetics in molecular intercalation superlattices. [PDF]

Sci Adv
Ueda T, Matsuoka H, Aoyagi S, Kitou S, Zhang Y, Kimura F, Hagiwara K, Sakano M, Iwagaki T, Nakamura Y, Ishizaka K, Machida T, Suda M, Arima TH, Kanazawa N.   +14 more
europepmc   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Continuous Snow-Cover Monitoring and Avalanche Detection with a Novel Sensor Array Box. [PDF]

Sensors (Basel)
Hoffmann M, Brauner M, Rachoy C, Dolleschal T, Reiweger I.   +4 more
europepmc   +1 more source

Single‐Vesicle Functional Nanophenotyping Reveals Heterogeneous PD‐L1 Accessibility in Triple‐Negative Breast Cancer

Small Methods, EarlyView.
Graphical Abstract. High‐speed atomic force microscopy enables real‐time, label‐free visualization of antibody interactions with individual extracellular vesicles. By quantifying binding frequency and dwell time, this approach reveals functional PD‐L1 accessibility that cannot be inferred from protein abundance alone, uncovering nanoscale heterogeneity
Reon Imakawa, Keesiang Lim, Takeshi Yoshida, Tomoyoshi Yamano, Tsunaki Hongu, Uryo Onishi, Masaharu Hazawa, Toshio Ando, Noriko Gotoh, Rikinari Hanayama, Richard W. Wong   +10 more
wiley   +1 more source

Near‐Atomic Investigation on the Elemental Redistribution During Coprecipitation of Nano‐Sized Kappa‐Type and B2 Precipitates in an Al‐Alloyed Lightweight Steel

steel research international, EarlyView.
Elemental redistribution during coprecipitation of kappa (κ)‐type and B2 precipitates in an Al‐alloyed lightweight steel is revealed by atom probe tomography (APT) and density functional theory (DFT). Fe and Ni redistribution promotes the evolution of B2 phase from NiAl‐type toward FeAl‐type and improves the stability of κ and B2 phases during ...
Bowen Zou, Yixu Wang, Xiao Shen, Philipp Krooß, Thomas Niendorf, Richard Dronskowski, Wenwen Song   +6 more
wiley   +1 more source

Atomistic Simulation of Loading Direction-Dependent Brittle-to-Ductile Transition in a ⟨110⟩-Oriented B2-FeAl Nanowire Under Bending. [PDF]

Nanomaterials (Basel)
Wei Z.
europepmc   +1 more source

Tailoring Microstructure and Hardness in Maraging 300 Steel via 2.4 wt.% Niobium Addition and Controlled Aging Treatments

steel research international, EarlyView.
High Nb (2.4 wt.%) addition to Maraging 300 steel drives lattice distortion and nanoscale Nb–Mo‐rich precipitation, confirmed by energy‐dispersive X‐ray spectroscopy mapping (Mo ~5.4 wt.%, Nb ~2.5 wt.%). Nanoindentation reveals strong matrix hardening (H >4.8 GPa) at 480°C aging, while 560°C induces ~1.92 vol.% reverted austenite, enabling tunable ...
Laylla Sharon B. Peixoto, Mohammad Masoumi, Luís Henrique N. de Lima, Marcos Natan da Silva Lima, Luis Flávio Gaspar Herculano, Isabel Ferreira de Barros, Geronimo Perez, Maria Vittoria Moraschini Reis, Hamilton Ferreira Gome Abreu, Marcelo J. Gomes da Silva   +9 more
wiley   +1 more source

Interactions between multi-species marine predator aggregations and the energy landscape. [PDF]

Philos Trans R Soc Lond B Biol Sci
Papastamatiou YP, Mourier J, Iosilevskii G.   +2 more
europepmc   +1 more source

Strain‐Induced NbC Precipitation as a Governing Mechanism for Hot Deformation Resistance in CrNiMnMoB Ultrahigh‐Strength Steels

steel research international, EarlyView.
Strain‐induced NbC precipitation governs hot‐deformation resistance in CrNiMnMoB ultrahigh‐strength steel by suppressing dynamic recrystallization, increasing activation energy, and refining martensitic substructures. The precipitation response is controlled by temperature, supersaturation, and strain rate, with slow deformation promoting extensive NbC
Atef Hamada, Ali Khosravifard, Khaled Elanany, Ahmed W. Abdelghany, Jukka Kömi, Pasi Suikkanen, Mohammed Ali   +6 more
wiley   +1 more source

Woven Eutectic Lamellar Structures Lead to Ultrahigh Strength and Energy Absorption Capacity in Additively Manufactured Lattice Structures

Small Structures, Volume 6, Issue 5, May 2025.
Herein, AlCoCrFeNi2.1 is selected to produce lattice structures by selective laser melting. The as‐printed lattice structures consist of numerous colonies of nanosized eutectic lamellar structures which are bent and interwind with each other to form a woven microstructure. The unique microstructure leads to unprecedented effective metal strength, yield
Zhiyong Ji, Xingyu Pan, Longlong Wang, Xintian Wang, Xu Chen, Hanwei Fu, Chunlei Qiu   +6 more
wiley   +1 more source