Results 51 to 60 of about 374,790 (294)
On 8 and 9 July 2018 extensive observations were conducted under fair-weather conditions in the German city of Stuttgart and its surroundings. This intensive observation period, part of the four weeks Urban Climate Under Change (UC)2 campaign, intended ...
Abdul Samad +14 more
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Temperature inversions prevent the mixing of air near the surface with the air higher in the atmosphere, contributing to high concentrations of air pollutants.
Peter Mlakar, Jana Faganeli Pucer
doaj +1 more source
TEMPERATURE INVERSIONS IN TRANSYLVANIA
This paper is based on meteorological stations data and statistical methods. Daily maximum and minimum temperatures (from the period 2004-2013) were studied from 22 meteorological stations of Transylvania (s.s.). Factor analysis reveals that temperature inversions are present mainly in winter.
openaire +2 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Conformal Bootstrap at Finite Temperature [PDF]
We initiate an approach to constraining conformal field theory (CFT) data at finite temperature using methods inspired by the conformal bootstrap for vacuum correlation functions. We focus on thermal one- and two-point functions of local operators on the
Iliesiu, Luca +4 more
core +3 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The O2 A-band night glow can be used to retrieve the temperature in the range of 80–120 km in the mesosphere and lower thermosphere (MLT). From the full spectrum of A-band night glow, the band used to retrieve temperature is selected based on the ...
Weijia Wang +3 more
doaj +1 more source
Doppler sodar observations of the winds and structure in the lower atmosphere over Fairbanks, Alaska [PDF]
Thesis (M.S.) University of Alaska Fairbanks, 2007Fairbanks, Alaska (64°49ʹ N, 147°52ʹ W) experiences strong temperature inversions which when combined with the low wind speeds prevailing during the winter cause serious air pollution problems. The SODAR (
Kankanala, Pavan Kumar Reddy
core
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source

