Results 91 to 100 of about 7,083,763 (260)

THE PROCEDURE OF REALIZATION OF THE DIDACTIC PRINCIPLE OF VISUAL METHOD IN AN EDUCATIONAL LABORATORY

open access: yesІнформаційні технології і засоби навчання, 2010
This paper is devoted to the procedure of realization of the main didactic principle – use visual method which becomes an essential factor of student perception of educational sources.
Anatolii H. Protasov
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Temperature Measurement System for Train Rheostat

open access: yes, 2013
This paper describes the development of a novel system for temperature measurement of train rheostats. These high resistances are used in train wagons to dissipate the power used to supply the train when it is braking.
A. Colombo   +5 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

A MULTICHANNEL FIBRE OPTIC TEMPERATURE MEASUREMENT SYSTEM

open access: yes, 2004
A novel approach to monitoring and control temperature in processes where conventional electrical methods are difficult or ineffective, such as in extremely hostile environments, in biological applications, or in presence of strong electromagnetic ...
GALLEANO R., FERNICOLA, VITO
core  

Ultrasonic distance sensor improvement using a two-level neural network [PDF]

open access: yes, 1995
This paper discusses the performance improvement that a neural network can provide to a contactless distance sensor based on the measurement of the time of flight (TOF) of an ultrasonic (US) pulse.
Ferraris, Franco   +13 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Temperature measurement and control system for transtibial prostheses: single subject clinical evaluation. [PDF]

open access: yes, 2016
The snug fit of a prosthetic socket over the residual limb can disturb thermal balance and put skin integrity in jeopardy by providing an unpleasant and infectious environment.
Leung, Aaron K L   +6 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Measurement of instantaneous temperature in shock-loaded nonmetallic solids

open access: yes, 1990
The feasibility of direct measurement of temperature in shock-loaded, nonmetallic solids within microseconds using a foil thermocouple of 200 Å thickness has been studied over a range of pressure from 0.5 to 4 GPa.
高举贤   +3 more
core   +1 more source

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