Results 51 to 60 of about 7,083,763 (260)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

A method for predicting IGBT junction temperature under transient condition [PDF]

, 2008
In this paper, a method to predict junction temperature of the solid-state switch under transient condition is presented. The method is based on the thermal model of the switch and instantaneous measurement of the energy loss in the device.
Putrus, G. A., HASH(0x55a67f690b00), Ahmed, Mohamed Mostafa Ramadan, G.A. Putrus, Putrus, Ghanim, M.M.R. Ahmed, Ahmed, M. M. R.   +6 more
core   +1 more source

Nonnegligible Temperature Drop Induced by Thermocouple on Samples in Gleeble Tests

Metals, 2023
High-temperature plastic deformation is one of the main methods for the fabrication of titanium-based alloys. Accurate determination of the mechanical constitutive relation is pivotal for the design, optimization, as well as the prediction of the ...
Xiuhong Zhao, Yuting Ma, Shuailong Gao, Xuexiong Li, Dejun Yu, Hao Wang   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Nanothermometry for cellular temperature monitoring and disease diagnostics

Interdisciplinary Medicine
Body temperature variations, including the generation, transfer, and dissipation of heat, play an important role throughout life and participate in all biological events.
Meilin Liu, Yaru Sun, Daniel Boon Loong Teh, Yi Zhang, Donglin Cao, Qingsong Mei   +5 more
doaj   +1 more source

Optimization of Temperature Measurement Method for High-Pressure Gas Flow Standard Facility Based on Sonic Nozzle Array

Aerospace
To improve the accuracy of the wind tunnel test, relying on the high-pressure gas source of the China Aerodynamic Research and Development Center, a secondary flow standard facility based on a sonic nozzle array was developed, with a pressure range of (1~
Zhihao Zhang, Jiaxi Zhao, Tingting Liu, Rongping Zhang   +3 more
doaj   +1 more source

Real-Time Two-Dimensional Mapping of Relative Local Surface Temperatures with a Thin-Film Sensor Array

Sensors, 2016
Dynamic mapping of an object’s local temperature distribution may offer valuable information for failure analysis, system control and improvement. In this letter we present a computerized measurement system which is equipped with a hybrid, low-noise ...
Gang Li, Zhenhai Wang, Xinyu Mao, Yinghuang Zhang, Xiaoye Huo, Haixiao Liu, Shengyong Xu   +6 more
doaj   +1 more source

A Continuously Worn Dual Temperature Sensor System for Accurate Monitoring of Core Body Temperature from the Ear Canal

Sensors, 2023
The objective of this work was to develop a temperature sensor system that accurately measures core body temperature from an ear-worn device. Two digital temperature sensors were embedded in a hearing aid shell along the thermal gradient of the ear canal
Kyle D. Olson, Parker O’Brien, Andy S. Lin, David A. Fabry, Steve Hanke, Mark J. Schroeder   +5 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Hydrogel Heart Model with Temperature Memory Properties for Surgical Simulation

Sensors, 2019
The continual development of surgical technology has led to a demand for surgical simulators for evaluating and improving the surgical technique of surgeons.
Hisataka Maruyama, Yuki Yokota, Keisuke Hosono, Fumihito Arai   +3 more
doaj   +1 more source