Results 51 to 60 of about 4,518,875 (307)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Polarization effects on the effective temperature of an ultracold electron source

New Journal of Physics, 2013
The influence has been studied of the ionization laser polarization on the effective temperature of an ultracold electron source, which is based on near-threshold photoionization. This source is capable of producing both high-intensity and high-coherence
W J Engelen, D J Bakker, O J Luiten, E J D Vredenbregt   +3 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Temperature-controlled terahertz polarization conversion bandwidth

Optics Express, 2021
Active control of metasurfaces has attracted widespread attention because of the adjustable electromagnetic properties obtained. Here we designed and experimentally studied a dynamically controllable polarization converter in the terahertz band. By designing the structural parameters and utilizing the insulator-to-metal phase transition of vanadium ...
Jing Zhao, Chunmei Ouyang, Xieyu Chen, Yanfeng Li, Caihong Zhang, Longcheng Feng, Biaobing Jin, Jiajun Ma, Yi Liu, Shoujun Zhang, Quan Xu, Jiaguang Han, Weili Zhang   +12 more
openaire   +2 more sources

NONLINEAR POLARIZATION SPECTROSCOPY (FREQUENCY DOMAIN) STUDIES OF EXCITED STATE PROCESSES: THE B800–850ANTENNA OF RHODOBACTER SPHAEROIDES [PDF]

, 1993
Nonlinear polarization spectroscopy in the frequency domain allows rate constant determinations of fast electronic energy and phase relaxations together with characterization of the type of line broadening.
Bandilla, M., Scheer, Hugo, Voigt, B., Michael Bandilla, Bernd Voigt, Pfeiffer, M., Dieter Leupold, Leupold, D., Michael Pfeiffer, Hugo Scheer   +9 more
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Twisted Hi-Bi fiber DFB lasers with controllable output polarization [PDF]

, 2012
We demonstrate that single polarization, hi-bi fiber DFB lasers are in general characterized by elliptical state of polarization, due to the in-built fiber birefringence axis rotation.
Richard Wilmshurst, Louise M. B. Walker, Michalis N. Zervas, Wilmshurst, R., Zervas, M.N., Walker, L.M.B.   +5 more
core   +2 more sources

Thermally Coupled CPV–DCMD System with Co-Designed Finned Microchannel Cooling and Baffled DCMD Channels

Technologies
Concentrated photovoltaic cooling and membrane distillation channel enhancement are commonly investigated as separate design problems, without considering the quality of the recovered heat available to the desalination unit.
Mohammed Rabie, Atia Khalifa
doaj   +1 more source

Temperature measurement in microchannel liquid flow by measuring fluorescence polarization

Nihon Kikai Gakkai ronbunshu, 2017
A fluid temperature measurement technique based on fluorescence polarization is developed and applied to measure the two-dimensional temperature distributions in microchannel.
Atsushi SUZUKI, Kazuya TATSUMI, Satoshi HORII, Reiko KURIYAMA, Kazuyoshi NAKABE   +4 more
doaj   +1 more source