Results 231 to 240 of about 3,634,731 (300)

Physiological Responses and Heat Tolerance Evaluation of Eight Varieties of <i>Primula vulgaris</i> Under Natural High Temperatures. [PDF]

Plants (Basel)
Li R, Yang J, Meng X, Cheng C, Zhang Y, Han X, Liu N, Zhao L, Qu Y, Tang T, Chen H, Li L, Shi Q.   +12 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Racial Disparities in Weather-Related Mortality in Virginia. [PDF]

Geohealth
DeGuzman PB, Novicoff WM, Ramos G, Pane MM, Johnson MC, Roney PC, Leigh HV, Basener W, Curran AL, DeMarcy B, Jang J, Schroeder C, Davis RE.   +12 more
europepmc   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Proof-of-concept thermoelectrically cooled sow-cooling mat. [PDF]

Sci Rep
Pan J, Shah SB, Leonard SM, Evans JO, Knauer MT, Saveliev AV.   +5 more
europepmc   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Proactive fault prediction in marine diesel engines using multivariate machine learning. [PDF]

Sci Rep
Michel M, Mehanna A, Saleh SN, Shehata AS.   +3 more
europepmc   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Temperature shapes the cold tolerance and body size of the springtail <i>Isotomiella minor</i> (Hexapoda, Collembola) in contrasting environments. [PDF]

Zookeys
Raschmanová N, Šustr V, Fedičová M, Hurka M, Žurovcová M, Kováč Ľ.   +5 more
europepmc   +1 more source

Apatite saturation revisited: new model formulations and applications to igneous rocks. [PDF]

Contrib Mineral Petrol
Klein BZ, Müntener O, Gillespie J, Marxer F.   +3 more
europepmc   +1 more source