Results 91 to 100 of about 73,973 (286)
Advanced Science, EarlyView.Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang +7 more
wiley +1 more source
O espaço da utopia em A Tempestade, de William Shakespeare
FronteiraZ, 2012 The Tempest is commonly referred to as “the most utopian” play by Shakespeare. In spite of that, the description of its utopian nature has not been grounded on fundamental concepts defined within the field of Utopian Studies.
Fátima Vieira
doaj +2 more sources
Shakespeare and 'Native Americans': forging identities through the 1916 Shakespeare Tercentenary [PDF]
, 2010 This article examines the celebrations organised for the 1916 Shakespeare Tercentenary in three American locations: Wellesley, MA; Atlanta, GA; and Grand Forks, ND.
Smialkowska, Monika
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Advanced Science, EarlyView.This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang +14 more
wiley +1 more source
Monarchy versus Liberal Democracy: A Study of Defense Mechanism in Shakespeare’s The Tempest and Lenny Abrahamson’s Room [PDF]
International Journal of English Language and Translation Studies, 2018 This paper, by employing comparative study, seeks to highlight the adoption of defense mechanism by analyzing the possible similarities and differences in the behaviors, and the strategies of the characters and the respective impact of the political ...
Ma’soomeh Sehat, Hossein Jahantigh
doaj
Advanced Science, EarlyView.HEK‐293T‐derived CD3ε Nb‐engineered EVs to generate dual‐targeting CAR‐T cells directly in vivo. These EVs selectively deliver CAR.BiTE transgenes into T cells and reprogramed to HLA‐G/PD‐L1‐targeting effector cells with enhanced memory and persistence.
Shi‐Wei Huang +27 more
wiley +1 more source
Advanced Science, EarlyView.Root lodging severely limits crop yield and quality. We reveal that ZmRLR1, a plasma membrane b‐type cytochrome, regulates lodging resistance in maize through dual roles: modulating intracellular redox balance and functioning as a novel component of clathrin‐mediated endocytosis to influence auxin homeostasis. Moreover, natural variations in the ZmRLR1
Wenshuai Lv +7 more
wiley +1 more source
Advanced Science, EarlyView.By encapsulating industrially relevant fabrics with dynamic imine networks, we show that the resulting composites exhibit exceptional oil absorbtion capability and chemical recyclability. It is poised for sustainable oil spill cleanup. ABSTRACT The development of high‐performance sorbents for oil spill remediation is highly desirable, which now calls ...
Changyi You +9 more
wiley +1 more source
«For thou must now know farther»
English Literature, 2014 Scholars in the last few decades have pointed out the manifold relations of Shakespeare’s The Tempest with the increasingly sceptical frame of mind of early modern English culture.
Squeo, Alessandra
doaj +1 more source