Results 101 to 110 of about 73,973 (286)
Endogenous Amplification of Apoptosis via p53 Regulation using a Cascade Nanocatalytic Medicine
Advanced Science, EarlyView.An engineered MOF nanomedicine (MAL) triggers cascade nanocatalysis in tumors, converting H2O2 and L‐Arg into cytotoxic peroxynitrite. This induces DNA damage, activates the p53 pathway, and amplifies mitochondrial apoptosis via the BAX/Bcl‐2/Caspase‐3 axis, effectively inhibiting colorectal cancer growth with high biocompatibility.
Tan Wu +8 more
wiley +1 more source
NamesTempest: Hurricane Naming and American Culture. By Liz Skilton. Baton Rouge: Louisiana State University Press. 2023. Pp. 320 (Paperback). $40.00. ISBN 13: 978-0-8071-7996-3.
Beth DiNatale Johnson
doaj +1 more source
You Will Oscar, You Will [PDF]
, 1991 The November 1990 Word Ways carried an article entitled The Shaming of the True by one Peter Newby - whoever he may be. His premise, supported by a series of non-anagrams, was to the effect that the film Kiss Me Kate was written by the actor whom he
Weepy, Bert N.
core +1 more source
Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders
Advanced Science, EarlyView.Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li +7 more
wiley +1 more source
Prospero's death: modernism, anti-humanism and Un re in ascolto [PDF]
, 2016 In his own comments, Luciano Berio has consistently rejected the term ‘opera’ for his Un re in ascolto (‘A King, listening’, 1979-84), instead insisting on calling it a ‘musical action’ (azione musicale). This dismissal of opera as a genre contrasts with
Heile, Bjorn
core
Advanced Science, EarlyView.To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li +9 more
wiley +1 more source
Advanced Science, EarlyView.A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu +15 more
wiley +1 more source
Evaluation Report of Prospero’s Island: an Immersive Approach to Literacy at Key Stage 3. [PDF]
, 2016 Prospero's Island is an immersive theatre project created by Punchdrunk Enrichment and sponsored by Learning Partner, London Borough of Hackney (Hackney Learning Trust).
Colvert, Angela +3 more
core
Advanced Science, EarlyView.A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo +8 more
wiley +1 more source